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  • The evolution of connectivity in metabolic networks. 

    Pfeiffer, Thomas; Soyer, Orkun S.; Bonhoeffer, Sebastian (Public Library of Science, 2005)
    Processes in living cells are the result of interactions between biochemical compounds in highly complex biochemical networks. It is a major challenge in biology to understand causes and consequences of the specific design ...
  • Evolution under Fluctuating Environments Explains Observed Robustness in Metabolic Networks 

    Soyer, Orkun S.; Pfeiffer, Thomas (Public Library of Science, 2010)
    A high level of robustness against gene deletion is observed in many organisms. However, it is still not clear which biochemical features underline this robustness and how these are acquired during evolution. One hypothesis, ...