Now showing items 23-42 of 1340

  • Alternative evolutionary paths to bacterial antibiotic resistance cause distinct collateral effects. 

    Barbosa, C; Trebosc, V; Kemmer, C; Rosenstiel, P; Beardmore, R; Schulenburg, H; Jansen, G (Oxford University Press, 2017-05-23)
    When bacteria evolve resistance against a particular antibiotic, they may simultaneously gain increased sensitivity against a second one. Such collateral sensitivity may be exploited to develop novel, sustainable antibiotic ...
  • Amplification of a cytochrome P450 gene is associated with resistance to neonicotinoid insecticides in the aphid Myzus persicae. 

    Puinean, AM; Foster, SP; Oliphant, L; Denholm, I; Field, LM; Millar, NS; Williamson, MS; Bass, C (Public Library of Science, 2010-06-24)
    The aphid Myzus persicae is a globally significant crop pest that has evolved high levels of resistance to almost all classes of insecticide. To date, the neonicotinoids, an economically important class of insecticides ...
  • Analysing animal social network dynamics: the potential of stochastic actor-oriented models 

    Fisher, DN; Ilany, A; Silk, MJ; Tregenza, T (Wiley for British Ecological Society, 2017-03)
    Animals are embedded in dynamically changing networks of relationships with conspecifics. These dynamic networks are fundamental aspects of their environment, creating selection on behaviours and other traits. However, ...
  • Analysis of climate paths reveals potential limitations on species range shifts 

    Early, Regan; Sax, Dov F. (Wiley, 2011)
    Forecasts of species endangerment under climate change usually ignore the processes by which species ranges shift. By analysing the 'climate paths' that range shifts might follow, and two key range-shift processes--dispersal ...
  • Analysis of known bacterial protein vaccine antigens reveals biased physical properties and amino acid composition 

    Mayers, Carl; Duffield, Melanie; Rowe, Sonya; Miller, Julie; Lingard, Bryan; Hayward, Sarah; Titball, Richard W. (Hindawi Publishing Corporation, 2003)
    Many vaccines have been developed from live attenuated forms of bacterial pathogens or from killed bacterial cells. However, an increased awareness of the potential for transient side-effects following vaccination has ...
  • An analysis of waves underlying grid cell firing in the medial enthorinal cortex 

    Wedgwood, KCA; Bonilla-Quintana, M; O'Dea, RD; Coombes, S (BioMed Central / SpringerOpen, 2017-08-25)
    Layer II stellate cells in the medial enthorinal cortex (MEC) express hyperpolarisation-activated cyclic-nucleotide-gated (HCN) channels that allow for rebound spiking via an Ih current in response to hyperpolaris- ing ...
  • Analysis of whole genome sequencing for the Escherichia coli O157:H7 typing phages 

    Cowley, Lauren A.; Beckett, Stephen J.; Chase-Topping, Margo; Perry, Neil; Dallman, Tim J.; Gally, David L.; Jenkins, Claire (BioMed Central, 2015-04-08)
    Background: Shiga toxin producing Escherichia coli O157 can cause severe bloody diarrhea and haemolytic uraemic syndrome. Phage typing of E. coli O157 facilitates public health surveillance and outbreak investigations, ...
  • The ancestral symbiont sensor kinase CSK links photosynthesis with gene expression in chloroplasts. 

    Puthiyaveetil, S; Kavanagh, TA; Cain, P; Sullivan, JA; Newell, CA; Gray, JC; Robinson, C; van der Giezen, M; Rogers, MB; Allen, John F. (2008-07-22)
    We describe a novel, typically prokaryotic, sensor kinase in chloroplasts of green plants. The gene for this chloroplast sensor kinase (CSK) is found in cyanobacteria, prokaryotes from which chloroplasts evolved. The CSK ...
  • Ancient diversification of eukaryotic MCM DNA replication proteins. 

    Aves, Stephen; Richards, Thomas A; Liu, Yuan (BioMed Central, 2009)
    Yeast and animal cells require six mini-chromosome maintenance proteins (Mcm2-7) for pre-replication complex formation, DNA replication initiation and DNA synthesis. These six individual MCM proteins form distinct heterogeneous ...
  • Animal Forests Through Time: Historical Data to Understand Present Changes in Marine Ecosystems 

    Thurstan, RH; Pandolfi, JM; zu Ermgassen, PSE (Springer, 2017)
    Animal forests form the foundation of many important marine benthic habitats. However, a near ubiquitous lack of long-term scientific data raises significant challenges in assessing how these communities have changed over ...
  • Animal minds: from computation to evolution. 

    Thornton, A; Clayton, Nicola S.; Grodzinski, U (Royal Society, 2012-10-05)
    In the great Darwinian struggle for existence, all animals must tackle the problems posed by variable environments, be it finding and processing food, recognizing and attracting potential mates, avoiding predators, ...
  • Animal personality: What are behavioural ecologists measuring? 

    Carter, Alecia J.; Feeney, WE; Marshall, Harry H.; Cowlishaw, Guy; Heinsohn, R (Wiley, 2013-05)
    The discovery that an individual may be constrained, and even behave sub-optimally, because of its personality type has fundamental implications for understanding individual- to group-level processes. Despite recent interest ...
  • Animating the Carbon Cycle 

    Schmitz, OJ; Raymond, PA; Estes, JA; Kurz, WA; Holtgrieve, GW; Ritchie, ME; Schindler, DE; Spivak, AC; Wilson, RW; Bradford, MA; Christensen, V; Deegan, L; Smetacek, V; Vanni, MJ; Wilmers, CC (Springer Verlag, 2013-09-19)
    Understanding the biogeochemical processes regulating carbon cycling is central to mitigating atmospheric CO2 emissions. The role of living organisms has been accounted for, but the focus has traditionally been on contributions ...
  • Anisotropic diffusion of spherical particles in closely confining microchannels 

    Dettmer, SL; Pagliara, S; Misiunas, K; Keyser, UF (American Physical Society, 2014-06)
    We present here the measurement of the diffusivity of spherical particles closely confined by narrow microchannels. Our experiments yield a two-dimensional map of the position-dependent diffusion coefficients parallel and ...
  • Annual Variation in Sterol Levels in Leaves of Taraxacum officinale Weber 1 

    Westerman, Lynne; Roddick, James G. (1981-10)
    Sterol levels in dandelion (Taraxacum officinale Weber) leaves were monitored over a period of 19 months. Sitosterol was the most abundant free sterol, followed by stigmasterol, then campesterol. Cholesterol could not be ...
  • Anthropogenic noise compromises antipredator behaviour in European eels. 

    Simpson, SD; Purser, J; Radford, AN (Wiley, 2014-08-06)
    Increases in noise-generating human activities since the Industrial Revolution have changed the acoustic landscape of many terrestrial and aquatic ecosystems. Anthropogenic noise is now recognized as a major pollutant of ...
  • Anthropogenic noise increases fish mortality by predation 

    Simpson, SD; Radford, AN; Nedelec, SL; Ferrari, MCO; Chivers, DP; McCormick, MI; Meekan, MG (Nature Publishing Group, 2016-02-05)
    Noise-generating human activities affect hearing, communication and movement in terrestrial and aquatic animals, but direct evidence for impacts on survival is rare. We examined effects of motorboat noise on post-settlement ...
  • Anthropogenic noise playback impairs embryonic development and increases mortality in a marine invertebrate. 

    Nedelec, SL; Radford, AN; Simpson, SD; Nedelec, B; Lecchini, D; Mills, SC (Nature Publishing Group, 2014-07-31)
    Human activities can create noise pollution and there is increasing international concern about how this may impact wildlife. There is evidence that anthropogenic noise may have detrimental effects on behaviour and physiology ...
  • Antibiotic Cycling and Antibiotic Mixing: which one best mitigates antibiotic resistance? 

    Beardmore, RE; Pena-Miller, R; Gori, F; Iredell, J (Oxford University Press, 2017-01-17)
    Can we exploit our burgeoning understanding of molecular evolution to slow the progress of drug resistance? One role of an infection clinician is exactly that: to foresee trajectories to resistance during antibiotic treatment ...
  • Antibiotic cycling versus mixing: the difficulty of using mathematical models to definitively quantify their relative merits. 

    Pena-Miller, R; Beardmore, Robert (American Institute of Mathematical Sciences, 2010-10)
    We ask the question Which antibiotic deployment protocols select best against drug-resistant microbes: mixing or periodic cycling? and demonstrate that the statistical distribution of the performances of both sets of ...