Now showing items 1-7 of 7

  • Ancient diversification of eukaryotic MCM DNA replication proteins. 

    Aves, Stephen; Richards, Thomas A; Liu, Yuan (BioMed Central, 2009)
    Yeast and animal cells require six mini-chromosome maintenance proteins (Mcm2-7) for pre-replication complex formation, DNA replication initiation and DNA synthesis. These six individual MCM proteins form distinct heterogeneous ...
  • DNA evidence for global dispersal and probable endemicity of protozoa 

    Bass, David; Richards, Thomas A; Matthai, Lena; Marsh, Victoria; Cavalier-Smith, Thomas (BioMed Central, 2007-09-13)
    Background It is much debated whether microbes are easily dispersed globally or whether they, like many macro-organisms, have historical biogeographies. The ubiquitous dispersal hypothesis states that microbes are so ...
  • Evolution and Classification of Myosins, a Paneukaryotic Whole-Genome Approach 

    Sebe-Pedros, A; Grau-Bove, X; Richards, Thomas A; Ruiz-Trillo, I (Oxford University Press, 2014-01-14)
    Myosins are key components of the eukaryotic cytoskeleton, providing motility for a broad diversity of cargoes. Therefore, understanding the origin and evolutionary history of myosin classes is crucial to address the ...
  • Horizontal gene transfer in osmotrophs: playing with public goods. 

    Richards, Thomas A; Talbot, Nicholas J. (2013-10)
    Osmotrophic microorganisms, such as fungi and oomycetes, feed by secreting depolymerizing enzymes to process complex food sources in the extracellular environment, and taking up the resulting simple sugars, micronutrients ...
  • Molecular diversity and distribution of marine fungi across 130 European environmental samples. 

    Richards, Thomas A; Leonard, G; Mahé, F; Del Campo, J; Romac, S; Jones, MD; Maguire, F; Dunthorn, M; De Vargas, C; Massana, R; Chambouvet, A (Royal Society, 2015-11-22)
    Environmental DNA and culture-based analyses have suggested that fungi are present in low diversity and in low abundance in many marine environments, especially in the upper water column. Here, we use a dual approach ...
  • REFGEN and TREENAMER: automated sequence data handling for phylogenetic analysis in the genomic era. 

    Leonard, Guy; Stevens, JR; Richards, Thomas A (Libertas Academica, 2009-05-06)
    The phylogenetic analysis of nucleotide sequences and increasingly that of amino acid sequences is used to address a number of biological questions. Access to extensive datasets, including numerous genome projects, means ...
  • A rhodopsin-guanylyl cyclase gene fusion functions in visual perception in a fungus 

    Avelar, GM; Schumacher, RI; Zaini, PA; Leonard, G; Richards, Thomas A; Gomes, Suely L. (Elsevier (Cell Press), 2014-06-02)
    Sensing light is the fundamental property of visual systems, with vision in animals being based almost exclusively on opsin photopigments [1]. Rhodopsin also acts as a photoreceptor linked to phototaxis in green algae [2, ...