Browsing University of Exeter Medical School by Title
Now showing items 55-74 of 1454
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Are rheumatoid factor, anti-citrullinated, and anti-carbamylated protein antibodies linked by post-translational modification of IgG?
(Wiley, 2016-08-02)No abstract is available. -
Are stem cell-derived neural cells physiologically credible?
(Wiley / Physiological Society, 2016-11-15)The fast emerging technological advances that are enabling biologists to convert stem cells from various sources into an ever-increasing variety of cell types unquestionably will have far-reaching implications for the ... -
Asking more of qualitative synthesis: a response to Sally Thorne
(SAGE Publications, 2017-05-25)We continue the conversation initiated by Sally Thorne’s observations about ‘metasynthetic madness’. We note that the variety of labels used to describe qualitative syntheses often reflect authors’ disciplines and geographical ... -
Assessing communication quality of consultations in primary care: initial reliability of the Global Consultation Rating Scale, based on the Calgary-Cambridge Guide to the Medical Interview.
(BMJ Publishing Group, 2014-03-06)OBJECTIVES: To investigate initial reliability of the Global Consultation Rating Scale (GCRS: an instrument to assess the effectiveness of communication across an entire doctor-patient consultation, based on the Calgary-Cambridge ... -
Assessing newborn body composition using principal components analysis: differences in the determinants of fat and skeletal size
(BioMed Central, 2006-08-17)BACKGROUND: Birth weight is a composite of skeletal size and soft tissue. These components are likely to have different growth patterns. The aim of this paper is to investigate the association between established determinants ... -
Assessing the accuracy of quantitative molecular microbial profiling
(MDPI, 2014-11-21)The application of high-throughput sequencing in profiling microbial communities is providing an unprecedented ability to investigate microbiomes. Such studies typically apply one of two methods: amplicon sequencing using ... -
Assessing the diagnostic accuracy of the identification of hyperkinetic disorders following the introduction of government guidelines in England
(BioMed Central, 2008-11-04)BACKGROUND: Previous studies have suggested that both underdiagnosis and overdiagnosis routinely occur in ADHD and hyperkinesis (hyperkinetic disorders). England has introduced governmental guidelines for these disorders' ... -
Assessing the effectiveness and cost effectiveness of subcutaneous nerve stimulation in patients with predominant back pain due to failed back surgery syndrome (SubQStim study): study protocol for a multicenter randomized controlled trial
(BioMed Central, 2013-06-25)Chronic radicular pain can be effectively treated with spinal cord stimulation, but this therapy is not always sufficient for chronic back pain. Subcutaneous nerve stimulation (SQS) refers to the placement of percutaneous ... -
Assessing the effectiveness of enhanced psychological care for patients with depressive symptoms attending cardiac rehabilitation compared with treatment as usual (CADENCE): study protocol for a pilot cluster randomised controlled trial
(BioMed Central, 2016-02-02)BACKGROUND: Around 17 % of people eligible for UK cardiac rehabilitation programmes following an acute coronary syndrome report moderate or severe depressive symptoms. While maximising psychological health is a core goal ... -
Assessing the impact of upper limb disability following stroke: a qualitative enquiry using internet-based personal accounts of stroke survivors
(Informa Healthcare, 2015)Purpose Upper limb disability following stroke may have multiple effects on the individual. Existing assessment instruments tend to focus on impairment and function and may miss other changes that are personally important. ... -
Assessment of endogenous insulin secretion in insulin treated diabetes predicts postprandial glucose and treatment response to prandial insulin
(BioMed Central, 2012-06-08)BACKGROUND: In patients with both Type 1 and Type 2 diabetes endogenous insulin secretion falls with time which changes treatment requirements, however direct measurement of endogenous insulin secretion is rarely performed. ... -
Assessment of practical classification guidelines for diabetes in insulin-treated patients
(Royal College of General Practitioners, 2016)Background Differentiating between Type 1(T1D) and Type 2 diabetes(T2D) is fundamental for appropriate treatment and management of patients, but can be challenging, especially when patients are insulin-treated. UK Practical ... -
Assessment of the HNF1B Score as a Tool to Select Patients for HNF1B Genetic Testing
(Karger, 2015-05-22)BACKGROUND/AIMS: Diagnosing hepatocyte nuclear factor 1β (HNF1B)-related disease is a challenging task due to the phenotypic variability and frequent absence of a family history. An HNF1B score has recently been developed ... -
An assessment of the impact of the NHS Health Technology Assessment Programme.
(NIHR Health Technology Assessment Programme, 2007-12)To consider how the impact of the NHS Health Technology Assessment (HTA) Programme should be measured. To determine what models are available and their strengths and weaknesses. To assess the impact of the first 10 years ... -
Assessment of therapeutic safety in systematic reviews: literature review
(BMJ, 2001-09-08) -
Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion.
(American Diabetes Association, 2015-06)A recent study identified a low-frequency variant at CCND2 associated with lower risk of type 2 diabetes, enhanced insulin response to a glucose challenge, higher height, and, paradoxically, higher BMI. We aimed to replicate ... -
Association Between Chronic Physical Conditions and the Effectiveness of Collaborative Care for Depression: An Individual Participant Data Meta-analysis.
(American Medical Association, 2016-08-17)IMPORTANCE: Collaborative care is an intensive care model involving several health care professionals working together, typically a physician, a case manager, and a mental health professional. Meta-analyses of aggregate ... -
The association between habitual physical activity and cigarette cravings, and influence of smokers’ characteristics in disadvantaged smokers not ready to quit
(Springer Verlag (Germany), 2016-06-02)Rationale Habitual physical activity (PA) may have an important role in suppressing cigarette cravings. Systematic reviews show a strong acute effect of bouts of PA on reducing cigarette cravings, and it may be that these ... -
The association between perseverative negative cognitive processes and negative affect in people with long term conditions: a protocol for systematic review and meta-analysis
(BioMed Central, 2014-01-06)BACKGROUND: Depression is common in people with long term conditions (LTCs) and is associated with worse medical outcomes. Understanding the mechanisms underpinning this relationship could help predict who is at increased ... -
Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes.
(BioMed Central, 2016-09-05)BACKGROUND: Activation of the renin-angiotensin-aldosterone-system (RAAS) has been proposed to contribute to development of vascular complications in type 2 diabetes (T2D). The aim of the present study was to determine if ...