Biclustering models for structured microarray data

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Biclustering models for structured microarray data

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dc.contributor.author Turner, Heather L. en_GB
dc.contributor.author Bailey, Trevor C. en_GB
dc.contributor.author Krzanowski, Wojtek J. en_GB
dc.contributor.author Hemingway, Cheryl A. en_GB
dc.contributor.department University of Exeter en_GB
dc.date.accessioned 2008-05-29T14:19:36Z en_GB
dc.date.accessioned 2011-01-25T10:33:33Z en_US
dc.date.accessioned 2013-03-20T12:28:05Z
dc.date.issued 2005 en_GB
dc.description.abstract Microarrays have become a standard tool for investigating gene function and more complex microarray experiments are increasingly being conducted. For example, an experiment may involve samples from several groups or may investigate changes in gene expression over time for several subjects, leading to large three-way data sets. In response to this increase in data complexity, we propose some extensions to the plaid model, a biclustering method developed for the analysis of gene expression data. This model-based method lends itself to the incorporation of any additional structure such as external grouping or repeated measures. We describe how the extended models may be fitted and illustrate their use on real data. en_GB
dc.identifier.citation 2 (4), pp. 316-329 en_GB
dc.identifier.doi 10.1109/TCBB.2005.49 en_GB
dc.identifier.uri http://hdl.handle.net/10036/28935 en_GB
dc.language.iso en en_GB
dc.publisher IEEE en_GB
dc.relation.url http://ieeexplore.ieee.org/search/wrapper.jsp?arnumber=1541984 en_GB
dc.relation.url http://dx.doi.org/10.1109/TCBB.2005.49 en_GB
dc.subject biclustering models en_GB
dc.subject gene expression en_GB
dc.subject gene function en_GB
dc.subject plaid model en_GB
dc.subject structured microarray data en_GB
dc.subject biclustering en_GB
dc.subject overlapping clustering en_GB
dc.subject partial supervision en_GB
dc.subject repeated measures en_GB
dc.subject three-way data en_GB
dc.subject two-way clustering en_GB
dc.title Biclustering models for structured microarray data en_GB
dc.type Article en_GB
dc.date.available 2008-05-29T14:19:36Z en_GB
dc.date.available 2011-01-25T10:33:33Z en_US
dc.date.available 2013-03-20T12:28:05Z
dc.identifier.issn 1545-5963 en_GB
dc.description ©2005 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE. en_GB
dc.identifier.journal IEEE/ACM Transactions on Computational Biology and Bioinformatics en_GB


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