Now showing items 1-3 of 3

  • Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts 

    Vimaleswaran, KS; Berry, DJ; Lu, C; Tikkanen, E; Pilz, S; Hiraki, LT; Cooper, JD; Dastani, Z; Li, R; Houston, DK; Wood, Andrew R.; Michaëlsson, K; Vandenput, L; Zgaga, L; Yerges-Armstrong, LM; McCarthy, MI; Dupuis, J; Kaakinen, M; Kleber, ME; Jameson, K; Arden, N; Raitakari, O; Viikari, J; Lohman, KK; Ferrucci, L; Melhus, H; Ingelsson, E; Byberg, L; Lind, L; Lorentzon, M; Salomaa, V; Campbell, H; Dunlop, Malcolm; Mitchell, BD; Herzig, KH; Pouta, A; Hartikainen, AL; Genetic Investigation of Anthropometric Traits-GIANT Consortium; Streeten, EA; Theodoratou, E; Jula, A; Wareham, NJ; Ohlsson, C; Frayling, Timothy M.; Kritchevsky, SB; Spector, TD; Richards, JB; Lehtimäki, T; Ouwehand, WH; Kraft, P; Cooper, Cyrus; März, W; Power, C; Loos, RJ; Wang, TJ; Järvelin, MR; Whittaker, JC; Hingorani, Aroon; Hyppönen, E (Public Library of Science, 2013)
    Obesity is associated with vitamin D deficiency, and both are areas of active public health concern. We explored the causality and direction of the relationship between body mass index (BMI) and 25-hydroxyvitamin D [25(OH)D] ...
  • Genetic determinants of serum testosterone concentrations in men 

    Ohlsson, C; Wallaschofski, H; Lunetta, KL; Stolk, L; Perry, John R.B.; Koster, A; Petersen, A-K; Eriksson, Joel; Lehtimäki, T; Huhtaniemi, IT; Hammond, GL; Maggio, M; Coviello, AD; Emas, SG; Ferrucci, L; Heier, M; Hofman, A; Holliday, KL; Jansson, J-O; Kähönen, M; Karasik, D; Karlsson, MK; Kiel, DP; Liu, Yongmei; Ljunggren, O; Lorentzon, M; Lyytikäinen, L-P; Meitinger, T; Mellström, D; Melzer, D; Miljkovic, I; Nauck, M; Nilsson, M; Penninx, BW; Pye, SR; Vasan, RS; Reincke, M; Rivadeneira, F; Tajar, A; Teumer, A; Uitterlinden, AG; Ulloor, J; Viikari, J; Völker, U; Völzke, H; Wichmann, HE; Wu, T-S; Zhuang, WV; Ziv, E; Wu, FCW; Raitakari, O; Eriksson, A; Bidlingmaier, M; Harris, Tamara; Murray, A; de Jong, FH; Murabito, JM; Bhasin, S; Vandenput, L; Haring, R (Public Library of Science, 2011)
    Testosterone concentrations in men are associated with cardiovascular morbidity, osteoporosis, and mortality and are affected by age, smoking, and obesity. Because of serum testosterone's high heritability, we performed a ...
  • A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation 

    Coviello, AD; Haring, R; Wellons, M; Vaidya, D; Lehtimäki, T; Keildson, S; Lunetta, KL; He, C; Fornage, M; Lagou, V; Mangino, M; Onland-Moret, NC; Chen, B; Eriksson, Joel; Garcia, M; Liu, YM; Koster, A; Lohman, K; Lyytikäinen, LP; Petersen, AK; Prescott, J; Stolk, L; Vandenput, L; Wood, Andrew R.; Zhuang, WV; Ruokonen, A; Hartikainen, AL; Pouta, A; Bandinelli, S; Biffar, R; Brabant, G; Cox, David G.; Chen, Y; Cummings, S; Ferrucci, L; Gunter, MJ; Hankinson, SE; Martikainen, H; Hofman, A; Homuth, G; Illig, T; Jansson, JO; Johnson, AD; Karasik, D; Karlsson, M; Kettunen, J; Kiel, DP; Kraft, P; Liu, J; Ljunggren, Ö; Lorentzon, M; Maggio, M; Markus, MR; Mellström, D; Miljkovic, I; Mirel, D; Nelson, S; Morin Papunen, L; Peeters, PH; Prokopenko, I; Raffel, L; Reincke, M; Reiner, AP; Rexrode, K; Rivadeneira, F; Schwartz, SM; Siscovick, D; Soranzo, N; Stöckl, D; Tworoger, S; Uitterlinden, AG; van Gils, CH; Vasan, RS; Wichmann, HE; Zhai, G; Bhasin, S; Bidlingmaier, M; Chanock, SJ; De Vivo, I; Harris, Tamara; Hunter, DJ; Kähönen, M; Liu, S; Ouyang, P; Spector, TD; van der Schouw, YT; Viikari, J; Wallaschofski, H; McCarthy, MI; Frayling, Timothy M.; Murray, A; Franks, S; Järvelin, MR; de Jong, FH; Raitakari, O; Teumer, A; Ohlsson, C; Murabito, JM; Perry, John R.B. (Public Library of Science, 2012)
    Sex hormone-binding globulin (SHBG) is a glycoprotein responsible for the transport and biologic availability of sex steroid hormones, primarily testosterone and estradiol. SHBG has been associated with chronic diseases ...