Institute of Medical Education: Recent submissions

Now showing items 66-70 of 299

    • The neuropeptide Pth2 dynamically senses others via mechanosensation 

      Anneser, L; Alcantara, IC; Gemmer, A; et al. (Nature Research, 2 December 2020)
      Species that depend on membership in social groups for survival exhibit changes in neuronal gene expression and behaviour when they face restricted social interactions or isolation1,2,3. Here we show that, across the ...

    • Circular RNAs: New players in Ageing and Age-related Chronic Disease 

      Haque, S (University of Exeter University of Exeter Medical School, 30 November 2020)
      Circular RNAs (circRNAs) are an emerging class of non-coding RNA that may regulate expression during normal and disease states. Although circRNAs accumulate in in vivo models of ageing, their role in this process and its ...

    • The Therapeutic Potential of Neuronal K-Cl Co-Transporter KCC2 in Huntington’s Disease and Its Comorbidities 

      Anfrews, K; Josiah, SS; Zhang, J (MDPI, 30 November 2020)
      Intracellular chloride levels in the brain are regulated primarily through the opposing effects of two cation-chloride co-transporters (CCCs), namely K+-Cl− co-transporter-2 (KCC2) and Na+-K+-Cl− co-transporter-1 (NKCC1). ...

    • Impaired speed encoding and grid cell periodicity in a mouse model of tauopathy 

      Ridler, T; Witton, J; Phillips, KG; et al. (eLife Sciences Publications, Ltd, 26 November 2020)
      Dementia is associated with severe spatial memory deficits which arise from dysfunction in hippocampal and parahippocampal circuits. For spatially sensitive neurons, such as grid cells, to faithfully represent the environment ...

    • Plantar Quad-Zone Analysis: A study of healthy feet 

      Wright, CJ; Collings, R; Morris, J; et al. (European Association of Thermology, 1 October 2020)
      The plantar aspect of the foot is a common site for pathology. Diabetic foot ulceration (DFU) and peripheral arterial disease (PAD) present the populations with the highest risk. Many people with diabetes experience foot ...