An alternative transdiagnostic mechanistic approach to affective disorders illustrated with research from clinical psychology
Author's draft version; post-print. Final version published by Sage available on Sage Journals Online http://online.sagepub.com/
Current psychiatric classification adopts a disorder-focused diagnostic approach, as exemplified within ICD-11 and DSM-V. Although this approach has improved reliability of categorisation, its validity and utility has been questioned (Harvey et al., 2004; Insel et al., 2009; Sanislow et al., 2010). Limitations include high co-morbidity between supposedly distinct disorders, heterogeneity within diagnoses, limited treatment efficacy, and similarities across disorders in aetiology, latent symptom structure, and underlying biology. There is also evidence of transdiagnostic cognitive-behavioural processes (Harvey et al., 2004). An alternative approach is therefore to focus on fundamental underlying mechanisms of psychopathology rather than observed symptom clusters. This paper considers the possible benefits, hurdles, and steps towards implementation of this transdiagnostic mechanistic approach, using the example of repetitive negative thought.
Copyright © 2015 by ISRE and SAGE
Vol. 7 (3), pp. 250-255