dc.contributor.author | Piacentini, MF | |
dc.contributor.author | Witard, OC | |
dc.contributor.author | Tonoli, C | |
dc.contributor.author | Jackman, SR | |
dc.contributor.author | Turner, JE | |
dc.contributor.author | Kies, AK | |
dc.contributor.author | Jeukendrup, AE | |
dc.contributor.author | Tipton, KD | |
dc.contributor.author | Meeusen, R | |
dc.date.accessioned | 2016-12-15T08:51:17Z | |
dc.date.issued | 2016-09 | |
dc.description.abstract | CONTEXT: Monitoring mood state is a useful tool for avoiding nonfunctional overreaching. Brain-derived neurotrophic factor (BDNF) is implicated in stress-related mood disorders. PURPOSE: To investigate the impact of intensified training-induced mood disturbance on plasma BDNF concentrations at rest and in response to exercise. METHODS: Eight cyclists performed 1 wk of normal (NT), 1 wk of intensified (INT), and 1 wk of recovery (REC) training. Fasted blood samples were collected before and after exercise on day 7 of each training week and analyzed for plasma BDNF and cortisol concentrations. A 24-item Profile of Mood State questionnaire was administered on day 7 of each training week, and global mood score (GMS) was calculated. RESULTS: Time-trial performance was impaired during INT (P = .01) and REC (P = .02) compared with NT. Basal plasma cortisol (NT = 153 ± 16 ng/mL, INT = 130 ± 11 ng/mL, REC = 150 ± 14 ng/ml) and BDNF (NT = 484 ± 122 pg/mL, INT = 488 ± 122 pg/mL, REC = 383 ± 56 pg/mL) concentrations were similar between training conditions. Likewise, similar exercise-induced increases in cortisol and BDNF concentrations were observed between training conditions. GMS was 32% greater during INT vs NT (P < .001). CONCLUSIONS: Consistent with a state of functional overreaching (FOR), impairments in performance and mood state with INT were restored after 1 wk of REC. These results support evidence for mood changes before plasma BDNF concentrations as a biochemical marker of FOR and that cortisol is not a useful marker for predicting FOR. | en_GB |
dc.description.sponsorship | DSM Food Specialties, Delft, The Netherlands funded this study. | en_GB |
dc.identifier.citation | Vol. 11, Iss. 6, pp. 824 - 830 | en_GB |
dc.identifier.doi | 10.1123/ijspp.2015-0279 | |
dc.identifier.other | 2015-0279 | |
dc.identifier.uri | http://hdl.handle.net/10871/24874 | |
dc.language.iso | en | en_GB |
dc.publisher | Human Kinetics | en_GB |
dc.relation.url | https://www.ncbi.nlm.nih.gov/pubmed/26658294 | en_GB |
dc.rights | © 2016 Human Kinetics, Inc. | en_GB |
dc.subject | cortisol | en_GB |
dc.subject | functional overreaching | en_GB |
dc.subject | neurotrophins | en_GB |
dc.subject | psychological mood state | en_GB |
dc.subject | trained cyclists | en_GB |
dc.title | Effect of Intensive Training on Mood With No Effect on Brain-Derived Neurotrophic Factor. | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2016-12-15T08:51:17Z | |
dc.identifier.issn | 1555-0265 | |
exeter.place-of-publication | United States | en_GB |
dc.description | Published | en_GB |
dc.description | Journal Article | en_GB |
dc.description | This is the author accepted manuscript. The final version is available from Human Kinetics via the DOI in this record. | en_GB |
dc.identifier.eissn | 1555-0273 | |
dc.identifier.journal | International Journal of Sports Physiology and Performance | en_GB |