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dc.contributor.authorWillis, TA
dc.contributor.authorWest, R
dc.contributor.authorRushforth, B
dc.contributor.authorStokes, T
dc.contributor.authorGlidewell, L
dc.contributor.authorCarder, P
dc.contributor.authorFaulkner, S
dc.contributor.authorFoy, R
dc.contributor.authorClamp, S
dc.contributor.authorFarrin, A
dc.contributor.authorHartley, S
dc.contributor.authorHulme, C
dc.contributor.authorLawton, R
dc.contributor.authorMcEachan, R
dc.contributor.authorRathfelder, M
dc.contributor.authorRichardson, J
dc.contributor.authorWard, V
dc.contributor.authorWatt, I
dc.date.accessioned2019-07-08T13:54:22Z
dc.date.issued2017-07-13
dc.description.abstractBackground: There are widely recognised variations in the delivery and outcomes of healthcare but an incomplete understanding of their causes. There is a growing interest in using routinely collected 'big data' in the evaluation of healthcare. We developed a set of evidence-based 'high impact' quality indicators (QIs) for primary care and examined variations in achievement of these indicators using routinely collected data in the United Kingdom (UK). Methods: Cross-sectional analysis of routinely collected, electronic primary care data from a sample of general practices in West Yorkshire, UK (n = 89). The QIs covered aspects of care (including processes and intermediate clinical outcomes) in relation to diabetes, hypertension, atrial fibrillation, myocardial infarction, chronic kidney disease (CKD) and 'risky' prescribing combinations. Regression models explored the impact of practice and patient characteristics. Clustering within practice was accounted for by including a random intercept for practice. Results: Median practice achievement of the QIs ranged from 43.2% (diabetes control) to 72.2% (blood pressure control in CKD). Considerable between-practice variation existed for all indicators: the difference between the highest and lowest performing practices was 26.3 percentage points for risky prescribing and 100 percentage points for anticoagulation in atrial fibrillation. Odds ratios associated with the random effects for practices emphasised this; there was a greater than ten-fold difference in the likelihood of achieving the hypertension indicator between the lowest and highest performing practices. Patient characteristics, in particular age, gender and comorbidity, were consistently but modestly associated with indicator achievement. Statistically significant practice characteristics were identified less frequently in adjusted models. Conclusions: Despite various policy and improvement initiatives, there are enduring inappropriate variations in the delivery of evidence-based care. Much of this variation is not explained by routinely collected patient or practice variables, and is likely to be attributable to differences in clinical and organisational behaviour.en_GB
dc.description.sponsorshipNational Institute for Health Research (NIHR)en_GB
dc.identifier.citationVol. 12 (7): e0177949en_GB
dc.identifier.doi10.1371/journal.pone.0177949
dc.identifier.grantnumberRP-PG-1209-10040en_GB
dc.identifier.urihttp://hdl.handle.net/10871/37898
dc.language.isoenen_GB
dc.publisherPublic Library of Scienceen_GB
dc.rightsCopyright: © 2017 Willis et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_GB
dc.subjectNSAIDsen_GB
dc.subjectprimary careen_GB
dc.subjectdiabetes mellitusen_GB
dc.subjectblood pressureen_GB
dc.subjectatrial fibrillationen_GB
dc.subjecthypertensionen_GB
dc.subjectchronic kidney diseaseen_GB
dc.subjectmyocardial infarctionen_GB
dc.titleVariations in achievement of evidence-based, high-impact quality indicators in general practice: An observational studyen_GB
dc.typeArticleen_GB
dc.date.available2019-07-08T13:54:22Z
dc.descriptionThis is the final version. Available from Public Library of Science via the DOI in this record.en_GB
dc.identifier.eissn1932-6203
dc.identifier.journalPLoS ONEen_GB
dc.rights.urihttp://www.rioxx.net/licenses/all-rights-reserveden_GB
dcterms.dateAccepted2017-05-05
rioxxterms.versionVoRen_GB
rioxxterms.licenseref.startdate2017-07-01
rioxxterms.typeJournal Article/Reviewen_GB
refterms.dateFCD2019-07-08T13:52:21Z
refterms.versionFCDVoR
refterms.dateFOA2019-07-08T13:54:26Z
refterms.panelAen_GB


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