1 August 2015 | Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.
| Kazlauskaite, A; Martínez-Torres, RJ; Wilkie, S; et al. |
18 June 2012 | Brain penetrant LRRK2 inhibitor
| Choi, Hwan Geun; Zhang, Jin-Wei; Deng, Xianming; et al. |
28 January 2012 | Characterization of TAE684 as a potent LRRK2 kinase inhibitor
| Zhang, J; Deng, X; Choi, HG; et al. |
20 May 2015 | Critical role of the SPAK protein kinase CCT domain in controlling blood pressure
| Zhang, J; Siew, K; Macartney, T; et al. |
20 May 2015 | Critical role of the SPAK protein kinase CCT domain in controlling blood pressure
| Zhang, J; Siew, K; Macartney, T; et al. |
14 May 2015 | Discovery of a Pyrrolopyrimidine (JH-II-127), a Highly Potent, Selective, and Brain Penetrant LRRK2 Inhibitor
| Hatcher, JM; Zhang, J; Choi, HG; et al. |
26 October 2016 | Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain
| Zhang, J; Gao, G; Begum, G; et al. |
26 October 2016 | Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain
| Zhang, J; Gao, G; Begum, G; et al. |
7 July 2012 | GSK2578215A; A potent and highly selective 2-arylmethyloxy-5-substitutent- N-arylbenzamide LRRK2 kinase inhibitor
| Reith, AD; Bamborough, P; Jandu, K; et al. |
1 June 2018 | Human With No Lysine Kinase 3 (WNK3): A Target Enabling Package (TEP)
| Pinkas, DM; Bufton, JC; Bartual, SG; et al. |
12 October 2012 | Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity
| Yao, C; Johnson, WM; Gao, Y; et al. |
8 March 2021 | Role of KLHL3 and dietary K+ in regulating KS-WNK1 expression
| Ostrosky-Frid, M; Chavez-Canales, M; Zhang, J; et al. |
4 March 2022 | Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase
| Chen, Z; Zhang, J; Murillo-de-Ozores, AR; et al. |
13 August 2018 | Structural and atropisomeric factors governing the selectivity of pyrimido-benzodiazipinones as inhibitors of kinases and bromodomains
| Wang, J; Erazo, T; Ferguson, FM; et al. |
15 March 2014 | The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters
| de Los Heros, P; Alessi, DR; Gourlay, R; et al. |
15 March 2014 | The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters
| de Los Heros, P; Alessi, DR; Gourlay, R; et al. |
15 July 2014 | The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters
| Alessi, DR; Zhang, J; Khanna, A; et al. |