Institute of Biomedical & Clinical Science
Recent Submissions
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Notch signaling coordinates ommatidial rotation in the Drosophila eye via transcriptional regulation of the EGF-Receptor ligand Argos
(Nature Research (Springer Nature), 9 December 2019)In all metazoans, a small number of evolutionarily conserved signaling pathways are reiteratively used during development to orchestrate critical patterning and morphogenetic processes. Among these, Notch (N) signaling is ... -
Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration
(Elsevier (Cell Press), 14 November 2019)Life on Earth emerged in a hydrogen sulfide (H2S)-rich environment eons ago and with it protein persulfidation mediated by H2S evolved as a signaling mechanism. Protein persulfidation (S-sulfhydration) is a post-translational ... -
Misannotation of multiple-nucleotide variants risks misdiagnosis
(F1000 Research Ltd, 9 January 2020)Multiple Nucleotide Variants (MNVs) are miscalled by the most widely utilised next generation sequencing analysis (NGS) pipelines, presenting the potential for missing diagnoses. These variants, which should be treated as ... -
Translational medicine: challenges and new orthopaedic vision (Mediouni-Model)
(Wolters Kluwer Health, 2020)In North America and three European countries translational medicine (TM) funding has taken center stage as the National Institutes of Health (NIH), for example, has come to recognize that delays are commonplace in completing ... -
Erratum. Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes. Diabetes 2014;63:3835–3845
(American Diabetes Association, 20 August 2015)In the article, there are two errors in the research design and methods section. In the section with the heading “Studies on Islet-Infiltrating Leukocytes,” the antibody listed as #M0701 should be attributed to Dako and ...