Institute of Biomedical & Clinical Science
Recent Submissions
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Lacosamide in the general population and in people with intellectual disability: Similar responses?
(Elsevier, 1 March 2020)Purpose: Epilepsy prevalence is significantly higher in people with Intellectual Disability (ID) compared to people with epilepsy (PWE) from the general population. Increased psychological and behavioural problems, healthcare ... -
A cross-sectional study on the prevalence of illness in coastal bathers compared to non-bathers in England and Wales: Findings from the Beach User Health Survey
(Elsevier, 9 March 2020)The risks of illness associated with bathing in UK coastal waters have not been quantified since the early 1990s. Efforts have been made since then to improve the quality of bathing waters. The aim of this study was to ... -
Impaired connectivity within neuromodulatory networks in multiple sclerosis and clinical implications
(Springer Verlag, 26 March 2020)There is mounting evidence regarding the role of impairment in neuromodulatory networks for neurodegenerative diseases, such as Parkinson’s and Alzheimer’s disease. However, the role of neuromodulatory networks in multiple ... -
Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis
(Springer Verlag, 15 March 2020)Aims/hypothesis: It is unclear whether type 1 diabetes is a single disease or if endotypes exist. Our aim was to use a unique collection of pancreas samples recovered soon after disease onset to resolve this issue. Methods: ... -
Hydrogen sulfide inhibits calcification of heart valves; implications for calcific aortic valve disease
(Wiley / British Pharmacological Society, 24 April 2019)Background and Purpose: Calcification of heart valves is a frequent pathological finding in chronic kidney disease and in elderly patients. Hydrogen sulfide (H2S) may exert anti-calcific actions. Here we investigated H2S ...