• Effect of Immobilisation on Neuromuscular Function In Vivo in Humans: A Systematic Review 

  Campbell, M; Varley-Campbell, J; Fulford, J; et al. (Springer Verlag, 21 March 2019)

  Background: Muscle strength loss following immobilisation has been predominantly attributed to rapid muscle atrophy. However, this cannot fully explain the magnitude of muscle strength loss, so changes in neuromuscular ...

• Genome-wide association study of microscopic colitis in the UK Biobank confirms immune-related pathogenesis 

  Green, HD; Beaumont, RN; Thomas, A; et al. (Oxford University Press (OUP) for European Crohn's and Colitis Organisation (ECCO), 24 May 2019)

  BACKGROUND AND AIMS: The causes of microscopic colitis are currently poorly understood. Previous reports have found clinical associations with coeliac disease and genetic associations at the HLA locus on the ancestral 8.1 ...

• RNA Biology Provides New Therapeutic Targets for Human Disease 

  Harries, LW (Frontiers, 8 March 2019)

  RNA is the messenger molecule that conveys information from the genome and allows the production of biomolecules required for life in a responsive and regulated way. Most genes are able to produce multiple mRNA products ...

• Obesity impacts the regulation of miR-10b and its targets in primary breast tumors 

  Meerson, A; Eliraz, Y; Yehuda, H; et al. (BMC, 18 January 2019)

  Background: Obesity increases breast cancer (BC) risk in post-menopausal women by mostly unknown molecular mechanisms which may partly be regulated by microRNAs (miRNAs). Methods: We isolated RNA from paired benign and ...

• Ambulance clinicians’ perceptions, assessment and management of frailty: thematic analysis of focus groups 

  Green, J; Kirby, K; Hope, SV (College of Paramedics, 1 December 2018)

  Introduction: More than half of all patients attended by the South Western Ambulance Service NHS Foundation Trust are over the age of 65. In 2017, 62% of older patients who were the subject of a frailty assessment were ...

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