• Associations between interarm differences in blood pressure and cardiovascular disease outcomes: protocol for an individual patient data meta-analysis and development of a prognostic algorithm 

  Clark, CE; Boddy, K; Warren, FC; et al. (BMJ Publishing Group, 2 July 2017)

  INTRODUCTION: Individual cohort studies in various populations and study-level meta-analyses have shown interarm differences (IAD) in blood pressure to be associated with increased cardiovascular and all-cause mortality. ...

• Arterial wall shear rate response to reactive hyperaemia is markedly different between young and older humans 

  Aizawa, K; Ramalli, A; Sbragi, S; et al. (Wiley / Physiological Society, 27 June 2019)

  KEY POINTS: The vasodilatory response to reactive hyperaemia is impaired with advancing age, but it is unclear whether this is because of an altered wall shear rate (WSR) stimulus or an altered flow-mediated dilatation ...

• Contralateral fatigue during severe-intensity single-leg exercise: influence of acute acetaminophen ingestion. 

  Morgan, PT; Bailey, SJ; Banks, RA; et al. (American Physiological Society, 29 May 2019)

  Exhaustive single-leg exercise has been suggested to reduce time to task failure (Tlim) during subsequent exercise in the contralateral leg by exacerbating central fatigue development. We investigated the influence of ...

• The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood. 

  Lee, BP; Pilling, LC; Bandinelli, S; et al. (Springer, 10 July 2019)

  Dysregulation of splicing factor expression is emerging as a driver of human ageing; levels of transcripts encoding splicing regulators have previously been implicated in ageing and cellular senescence both in vitro and ...

• Cathepsin L-induced galectin-1 may act as a proangiogenic factor in the metastasis of high-grade serous carcinoma 

  Pranjol, MZI; Zinovkin, DA; Maskell, ART; et al. (BMC (Springer Nature), 3 July 2019)

  Background:New treatment options for metastasised high-grade serous carcinoma (HGSC) are urgently needed. HGSC frequently metastasises to the omentum, inducing angiogenesis in the local omental microvasculature to facili-tate ...

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