• Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage 

  Sioofy-Khojine, A-B; Richardson, SJ; Locke, JM; et al. (Springer, 22 July 2022)

  AIMS/HYPOTHESIS: Enteroviral infection has been implicated consistently as a key environmental factor correlating with the appearance of autoimmunity and/or the presence of overt type 1 diabetes, in which pancreatic ...

• Detection of antiviral tissue responses and increased cell stress in the pancreatic islets of newly diagnosed Type 1 diabetes patients: results from the DiViD study 

  Krogvold, L; Leete, P; Mynarek, IM; et al. (Frontiers Media, 26 July 2022)

  Aims/hypothesis: The Diabetes Virus Detection (DiViD) study has suggested the presence of low-grade enteroviral infection in pancreatic tissue collected from six of six live adult patients newly diagnosed with type 1 ...

• A biallelic loss-of-function PDIA6 variant in a second patient with polycystic kidney disease, infancy-onset diabetes, and microcephaly 

  De Franco, E; Wakeling, MN; Frew, RD; et al. (Wiley, 18 July 2022)

  We report a second patient with intrauterine growth retardation, congenital polycystic kidney disease, infancy-onset diabetes, microcephaly, and liver fibrosis caused by a homozygous PDIA6 loss-of-function variant. Our ...

• Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial. 

  RESTART Collaboration (Elsevier, 22 May 2019)

  BACKGROUND: Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype ...

• Antifungal Exposure and Resistance Development: Defining Minimal Selective Antifungal Concentrations and Testing Methodologies 

  Stevenson, EM; Gaze, WH; Gow, NAR; et al. (Frontiers Media, 13 June 2022)

  This scoping review aims to summarise the current understanding of selection for antifungal resistance (AFR) and to compare and contrast this with selection for antibacterial resistance, which has received more research ...

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