Institute of Medical Education: Recent submissions
Now showing items 146-150 of 299
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Outcome of cell suspension allografts in a patient with Huntington's disease
(Wiley, 25 October 2018)For patients with incurable neurodegenerative disorders such as Huntington's (HD) and Parkinson's disease, cell transplantation has been explored as a potential treatment option. Here, we present the first clinicopathological ... -
Intravenous immunoglobulin and rituximab versus placebo treatment of antibody-associated psychosis: Study protocol of a randomised phase IIa double-blinded placebo-controlled trial (SINAPPS2)
(BMC, 7 June 2019)Background: Evidence is conflicting about a causal role of inflammation in psychosis and, specifically, regarding antibodies binding to neuronal membrane targets, especially N-methyl-D-aspartate receptors. NMDAR, LGI1 and ... -
Understanding student radiographer attrition: Risk factors and strategies
(Elsevier for College of Radiographers, 23 December 2019)Introduction Diagnostic student radiographer attrition is reported at 14%, 6% higher than the average for higher education, however, little research has been undertaken on this subject. This study explored risk factors ... -
Selection for antibiotic resistance in complex microbial communities
(University of Exeter Medical School, 13 January 2020)Measureable concentrations of antibiotics are released into the environment from anthropogenic sources. Environmental risk assessment investigates the risks these concentrations pose to aquatic life but does not determine ... -
Modulation of brain cation-Cl− cotransport via the SPAK kinase inhibitor ZT-1a
(Nature Research (part of Springer Nature), 7 January 2020)The SLC12A cation-Clcotransporters (CCC), including NKCC1 and the KCCs, are important determinants of brain ionic homeostasis. SPAK kinase (STK39) is the CCC master regulator, which stimulates NKCC1 ionic influx and inhibits ...