Frequency of Th17 CD20+ cells in the peripheral blood of rheumatoid arthritis patients is higher compared to healthy subjects
Eggleton, P; Bremer, E; Tarr, J.M.; et al.de Bruyn, M; Helfrich, W; Kendall, A; Haigh, Richard; Viner, N.J.; Winyard, Paul G.
Date: 15 December 2011
Article
Journal
Arthritis Research and Therapy
Publisher
BMC
Publisher DOI
Abstract
Rheumatoid arthritis (RA) is considered a T cell driven autoimmune disease, therefore, the ability of B cell depleting biologics, e.g., anti-CD20 antibodies, to alleviate RA is unclear. This study examined the proportions of IL-17-secreting lymphocytes in the blood of healthy subjects and RA patients and determined if Th17 cells belong ...
Rheumatoid arthritis (RA) is considered a T cell driven autoimmune disease, therefore, the ability of B cell depleting biologics, e.g., anti-CD20 antibodies, to alleviate RA is unclear. This study examined the proportions of IL-17-secreting lymphocytes in the blood of healthy subjects and RA patients and determined if Th17 cells belong to a CD20+ subset of T cells.
Peninsula College of Medicine and Dentistry: Medicine
Collections of Former Colleges
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