Frequency of Th17 CD20+ cells in the peripheral blood of rheumatoid arthritis patients is higher compared to healthy subjects.
de Bruyn, M
Winyard, Paul G.
Arthritis Research and Therapy
Rheumatoid arthritis (RA) is considered a T cell driven autoimmune disease, therefore, the ability of B cell depleting biologics, e.g., anti-CD20 antibodies, to alleviate RA is unclear. This study examined the proportions of IL-17-secreting lymphocytes in the blood of healthy subjects and RA patients and determined if Th17 cells belong to a CD20+ subset of T cells.
addresses: Peninsula Medical School, University of Exeter, Heavitree Road, Exeter EX1 2LU, UK. email@example.com
notes: PMCID: PMC3334661
types: Journal Article; Research Support, Non-U.S. Gov't
Vol. 13, Issue 6, pp. R208 -
Place of publication