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dc.contributor.authorWadey, CA
dc.contributor.authorWeston, ME
dc.contributor.authorDorobantu, DM
dc.contributor.authorTaylor, RS
dc.contributor.authorPieles, GE
dc.contributor.authorBarker, AR
dc.contributor.authorWilliams, CA
dc.date.accessioned2020-09-07T12:38:50Z
dc.date.issued2020-09-07
dc.description.abstractBackground Numerous studies have measured the prognostic associations between cardiorespiratory fitness and patient outcomes in congenital heart disease, but no systematic review has assessed these associations for all types of congenital heart disease. It is therefore a timely opportunity to syntheses all available data using a systematic review methodology. The aim of this study is to detail the protocol for a systematic review and meta-analysis. Objectives Within this paper we have developed a protocol for a prognostic factors systematic review and meta-analysis, to assess the role of cardiopulmonary exercise testing/cardiorespiratory fitness, in the prognosis of mortality and morbidity in congenital heart disease. Methods We have outlined, in detail, the process for this systematic review using the latest accepted methodological guidelines for prognostic factors research, such as the PICOTS system, CHARMS-PF data extraction, QUIPS risk of bias assessments and the prognostic GRADE guidelines (see list of abbreviations). Conclusion The implications of this review will aid future treatments, interventions and individual patient risk prediction. The publication of this protocol aims to improve scientific rigour by ensuring transparency in the systematic review and meta-analysis process.en_GB
dc.description.sponsorshipCanon Medical Systems UK Ltd.en_GB
dc.description.sponsorshipUniversity of Exeteren_GB
dc.description.sponsorshipQUEX instituteen_GB
dc.description.sponsorshipMedical Research Councilen_GB
dc.identifier.citationVol. 4, 4en_GB
dc.identifier.doi10.1186/s40949-020-00035-x
dc.identifier.urihttp://hdl.handle.net/10871/122748
dc.language.isoenen_GB
dc.publisherBMCen_GB
dc.rights© The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.en_GB
dc.subjectSystematic reviewen_GB
dc.subjectCardiorespiratory fitnessen_GB
dc.subjectExercise testen_GB
dc.subjectMortalityen_GB
dc.subjectMorbidityen_GB
dc.subjectCongenital hearten_GB
dc.subjectPrognosisen_GB
dc.titleThe role of cardiopulmonary exercise testing (CPET) in predicting mortality and morbidity in people with congenital heart disease: a systematic review and meta-analysis (Protocol)en_GB
dc.typeArticleen_GB
dc.date.available2020-09-07T12:38:50Z
exeter.article-number4en_GB
dc.descriptionThis is the final version. Available from BMC via the DOI in this record.en_GB
dc.identifier.eissn2056-7251
dc.identifier.journalJournal of Congenital Cardiologyen_GB
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_GB
dcterms.dateAccepted2020-07-28
rioxxterms.versionVoRen_GB
rioxxterms.licenseref.startdate2020-07-28
rioxxterms.typeJournal Article/Reviewen_GB
refterms.dateFCD2020-09-07T12:35:01Z
refterms.versionFCDVoR
refterms.dateFOA2020-09-07T12:38:55Z
refterms.panelCen_GB


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© The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License,
which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give
appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if
changes were made. The images or other third party material in this article are included in the article's Creative Commons
licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons
licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain
permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the
data made available in this article, unless otherwise stated in a credit line to the data.
Except where otherwise noted, this item's licence is described as © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.