The Role of Speckle Tracking Echocardiography in the Evaluation of Common Inherited Cardiomyopathies in Children and Adolescents: A Systematic Review
dc.contributor.author | Dorobantu, DM | |
dc.contributor.author | Wadey, CA | |
dc.contributor.author | Amir, NH | |
dc.contributor.author | Stuart, AG | |
dc.contributor.author | Williams, CA | |
dc.contributor.author | Pieles, GE | |
dc.date.accessioned | 2021-04-01T13:43:31Z | |
dc.date.issued | 2021-04-01 | |
dc.description.abstract | Speckle tracking echocardiography (STE) has gained importance in the evaluation of adult inherited cardiomyopathies, but its utility in children is not well characterized. We conducted a systematic review to evaluate the role of STE in pediatric inherited cardiomyopathies. PubMed, EMBASE, Web of Science, Scopus, CENTRAL and CINAHL databases were searched up to May 2020, for terms related to inherited cardiomyopathies and STE. Included were dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), left ventricular non-compaction (LVNC) and arrhythmogenic cardiomyopathy (ACM). A total of 14 cohorts were identified, of which six were in DCM, four in HCM, three in LVNC and one in ACM. The most commonly reported STE measurements were left ventricular longitudinal strain (Sl), circumferential strain (Sc), radial strain (Sr) and rotation/torsion/twist. Sl, Sc and were abnormal in all DCM and LVNC cohorts, but not in all HCM. Apical rotation and twist/torsion were increased in HCM, and decreased in LVNC. Abnormal STE parameters were reported even in cohorts with normal non-STE systolic/diastolic measurements. STE in childhood cardiomyopathies can detect early changes which may not be associated with changes in cardiac function detectable by non-STE methods. Longitudinal and circumferential strain should be introduced in the cardiomyopathy echocardiography protocol, reflecting current practice in adults. | en_GB |
dc.description.sponsorship | Medical Research Council (MRC) | en_GB |
dc.description.sponsorship | Majlis Amanah Rakyat (MARA) | en_GB |
dc.description.sponsorship | University of Exeter | en_GB |
dc.description.sponsorship | Canon Medical Systems UK Ltd. | en_GB |
dc.identifier.citation | Vol. 11 (4), article 635 | en_GB |
dc.identifier.doi | 10.3390/diagnostics11040635 | |
dc.identifier.grantnumber | MR/N0137941/1 | en_GB |
dc.identifier.uri | http://hdl.handle.net/10871/125284 | |
dc.language.iso | en | en_GB |
dc.publisher | MDPI | en_GB |
dc.rights | © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | en_GB |
dc.subject | speckle tracking echocardiography | en_GB |
dc.subject | pediatric inherited cardiomyopathy | en_GB |
dc.subject | dilated cardiomyopathy | en_GB |
dc.subject | hypertrophic cardiomyopathy | en_GB |
dc.subject | left ventricular non-compaction | en_GB |
dc.subject | arrhythmogenic cardiomyopathy | en_GB |
dc.title | The Role of Speckle Tracking Echocardiography in the Evaluation of Common Inherited Cardiomyopathies in Children and Adolescents: A Systematic Review | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2021-04-01T13:43:31Z | |
dc.description | This is the final version. Available on open access from MDPI via the DOI in this record | en_GB |
dc.description | Data Availability Statement: Data available on request. | en_GB |
dc.identifier.eissn | 2075-4418 | |
dc.identifier.journal | Diagnostics | en_GB |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_GB |
dcterms.dateAccepted | 2021-03-12 | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2021-04-01 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2021-04-01T13:39:45Z | |
refterms.versionFCD | VoR | |
refterms.dateFOA | 2021-04-01T13:43:40Z | |
refterms.panel | C | en_GB |
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Except where otherwise noted, this item's licence is described as © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).