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dc.contributor.authorCraig, M
dc.contributor.authorPennacchia, A
dc.contributor.authorWright, NR
dc.contributor.authorChase, HW
dc.contributor.authorHogarth, L
dc.date.accessioned2017-02-14T08:50:24Z
dc.date.issued2011-07-28
dc.description.abstractIt is currently unclear how effective un-medicated, self-paced alcohol withdrawal is in reducing alcohol consumption in alcohol dependent clients. To address this question, the current study examined the reduction in alcohol consumption, assessed by breath alcohol and drink diary self-report, of 405 alcohol-dependent clients over a 10-day, un-medicated, self-paced alcohol reduction program that included group discussion of strategies for titrating between withdrawal and intoxication. It was found that attendance at treatment sessions was associated with a reduction in alcohol consumption, reflected in both breath alcohol and diary measures, and these two measures were significantly correlated. Overall, 35% of clients achieved a zero breath alcohol reading by their final session, although this percentage increased to 56% of clients who attended all 10 sessions. Withdrawal seizures occurred in only 0.5% of clients despite 17.2% having a history of seizures in other settings. It is concluded that the alcohol reduction protocol outlined here provides an effective and safe method for reducing alcohol consumption in severely alcohol dependent clients, and that methods for augmenting attendance, such as contingency management, should enhance the effectiveness of this treatment.en_GB
dc.description.sponsorshipThe academic contribution of LH and HWC was supported by an MRC (http://www.mrc.ac.uk/Fundingopportunities/Grants/index.htm) grant (# G0701456) held by LH at the University of Nottingham. The treatment protocols run by MC and AP were funded by the Nottinghamshire Healthcare NHS Trust (http://www.nottinghamshirehealthcare.nhs.uk/). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.en_GB
dc.identifier.citationVol. 6, Iss. 7, pp. e22994 -en_GB
dc.identifier.doi10.1371/journal.pone.0022994
dc.identifier.otherPONE-D-10-05660
dc.identifier.urihttp://hdl.handle.net/10871/25814
dc.language.isoenen_GB
dc.publisherPublic Library of Scienceen_GB
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pubmed/21829573en_GB
dc.rightsCopyright: © 2011 Craig et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_GB
dc.subjectAdulten_GB
dc.subjectAlcohol Drinkingen_GB
dc.subjectBreath Testsen_GB
dc.subjectEthanolen_GB
dc.subjectFemaleen_GB
dc.subjectHumansen_GB
dc.subjectMaleen_GB
dc.subjectSelf Careen_GB
dc.subjectSubstance Withdrawal Syndromeen_GB
dc.titleEvaluation of un-medicated, self-paced alcohol withdrawal.en_GB
dc.typeArticleen_GB
dc.date.available2017-02-14T08:50:24Z
exeter.place-of-publicationUnited Statesen_GB
dc.descriptionPublisheden_GB
dc.descriptionEvaluation Studiesen_GB
dc.descriptionJournal Articleen_GB
dc.descriptionResearch Support, Non-U.S. Gov'ten_GB
dc.descriptionThis is the final version of the article. Available from Public Library of Science via the DOI in this record.en_GB
dc.identifier.eissn1932-6203
dc.identifier.journalPLoS Oneen_GB


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