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dc.contributor.authorHogarth, L
dc.contributor.authorSeedat, S
dc.contributor.authorMartin, L
dc.date.accessioned2018-10-18T13:33:27Z
dc.date.issued2018-10-30
dc.description.abstractBackground: In adults, it has been shown that the relationship between childhood abuse and substance misuse problems is mediated by the belief that substance use helps cope with negative affective states. By contrast, in adolescents, it is unknown whether drug use coping motives play this same mediating role. Methods: Secondary analysis of 1149 school attending adolescents in Cape Town South Africa (average age = 16.24 years, range = 13–23; 60% females). Questionnaire measures obtained during a single test session (among a larger battery) assessed childhood trauma (CTQ), alcohol (AUDIT) and drug problems (DUDIT), and coping orientation (A-COPE) which contained three items assessing drug use to cope with negative affect. Results: The three types of childhood abuse measured by the CTQ – emotional, physical and sexual – were positively associated with greater alcohol/drug problems, and drug use coping motives. Drug use coping motives mediated the relationships between childhood abuse types and alcohol/drug problems, and these mediational pathways remained significant when gender and other subscales of the A-COPE were included as covariates. Conclusions: These data are preliminary insofar as drug use coping motives were assessed with a non-validated subscale of the A-COPE. Nevertheless, drug use to cope with negative affect mediated the relationship between all three types of childhood abuse (emotional, physical, sexual) and alcohol/drug problems in school attending adolescents. The implication is that drug prevention programs for this age group should seek to mitigate drug use coping motives.en_GB
dc.description.sponsorshipThe secondary analysis was supported by an MRC Confidence in Global Mental Health pump priming award (MC_PC_MR/R019991/1) to Hogarth and Seedat, and by an Alcohol Research UK grant (RS17/03) to Hogarth. The original study that collected the data was supported by the South African Research Chair in PTSD, hosted by Stellenbosch University, funded by the Department of Science and Technology, Republic of South Africa (Grant No. 64811) and administered by the National Research Foundation, to Seedat and Martin.en_GB
dc.identifier.citationVol. 194, pp. 69-74.en_GB
dc.identifier.doi10.1016/j.drugalcdep.2018.10.009
dc.identifier.urihttp://hdl.handle.net/10871/34346
dc.language.isoenen_GB
dc.publisherElsevier / College on Problems of Drug Dependenceen_GB
dc.rights© 2018 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/BY/4.0/).
dc.subjectChildhood abuseen_GB
dc.subjectSubstance use coping motivesen_GB
dc.subjectAlcohol dependenceen_GB
dc.subjectDrug use problemsen_GB
dc.subjectMediation analysisen_GB
dc.titleRelationship between childhood abuse and substance misuse problems is mediated by substance use coping motives, in school attending South African adolescentsen_GB
dc.typeArticleen_GB
dc.identifier.issn0376-8716
dc.descriptionThis is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record.en_GB
dc.identifier.journalDrug and Alcohol Dependenceen_GB


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