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dc.contributor.authorNelis, SM
dc.contributor.authorWu, Y-T
dc.contributor.authorMatthews, FE
dc.contributor.authorMartyr, A
dc.contributor.authorQuinn, C
dc.contributor.authorRippon, I
dc.contributor.authorRusted, J
dc.contributor.authorThom, JM
dc.contributor.authorKopelman, MD
dc.contributor.authorHindle, JV
dc.contributor.authorJones, RW
dc.contributor.authorClare, L
dc.date.accessioned2018-11-16T14:41:15Z
dc.date.issued2018-11-07
dc.description.abstractBackground: The aim was to investigate the comorbidity profile of people with dementia and examine the associations between severity of comorbidity, health-related quality of life (HRQoL) and quality of life (QoL). Methods: The improving the experience of Dementia and Enhancing Active Life (IDEAL) cohort consisted of 1,547 people diagnosed with dementia who provided information on the number and type of comorbid conditions. Participants also provided ratings of their health-related and dementia-specific QoL. Results: The majority of the sample were living with more than one chronic condition. Hypertension was commonly reported and frequently combined with connective tissue disease, diabetes and depression. The number of comorbid conditions was associated with low QoL scores, and those with severe comorbidity (≥5 conditions) showed the greatest impact on their well-being. Conclusions: Comorbidity is an important risk factor for poor QoL and health status in people with dementia. Greater recognition of the nature and impact of comorbidity is needed to inform support and interventions for people with dementia and a multidisciplinary approach to care provision is recommended.en_GB
dc.description.sponsorshipThe IDEAL study is funded by the Economic and Social Research Council (UK) and the National Institute for Health Research (UK) through grant ES/L001853/2 ‘Improving the experience of dementia and enhancing active life: living well with dementia’ (Investigators: L. Clare, I.R. Jones, C. Victor, J.V. Hindle, R.W. Jones, M. Knapp, M. D. Kopelman, R. Litherland, A. Martyr, F. Matthews, R.G. Morris, S.M. Nelis, J. Pickett, C. Quinn, J. Rusted, J. Thom).en_GB
dc.identifier.citationPublished online 7 November 2018en_GB
dc.identifier.doi10.1093/ageing/afy155
dc.identifier.urihttp://hdl.handle.net/10871/34795
dc.language.isoenen_GB
dc.publisherOxford University Press (OUP) for British Geriatrics Societyen_GB
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pubmed/30403771en_GB
dc.rights© The Author(s) 2018. Published by Oxford University Press on behalf of the British Geriatrics Society. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.en_GB
dc.subjectAlzheimer’sen_GB
dc.subjectmultimorbiditiesen_GB
dc.subjectdepressionen_GB
dc.subjectolder peopleen_GB
dc.titleThe impact of comorbidity on the quality of life of people with dementia: findings from the IDEAL studyen_GB
dc.typeArticleen_GB
dc.date.available2018-11-16T14:41:15Z
exeter.place-of-publicationEnglanden_GB
dc.descriptionThis is the final version. Available on open access from OUP via the DOI in this recorden_GB
dc.descriptionData access: The research materials supporting this publication will be made accessible through the UK Data Archive (http://www.data-archive.ac.uk/) in 2019.en_GB
dc.identifier.journalAge and Ageingen_GB


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