The Potential Impact of Displacing Sedentary Time in Adults with Type 2 Diabetes.
dc.contributor.author | Falconer, CL | |
dc.contributor.author | Page, AS | |
dc.contributor.author | Andrews, RC | |
dc.contributor.author | Cooper, AR | |
dc.date.accessioned | 2019-01-30T11:31:04Z | |
dc.date.issued | 2015-10-01 | |
dc.description.abstract | PURPOSE: Sedentary time, in particular, prolonged unbroken sedentary time, is detrimental to health and displaces time spent in either light or moderate intensity physical activity. This cross-sectional study aimed to identify the potential impact of reallocating time from sedentary behaviors to more active behaviors on measures of body composition and metabolic health in people with type 2 diabetes. METHODS: Participants were 519 adults with newly diagnosed type 2 diabetes who had been recruited to the Early Activity in Diabetes (Early ACTID) randomized controlled trial. Waist-worn accelerometers were used to obtain objective measurement of sedentary time, light physical activity (LPA), and moderate-to-vigorous physical activity (MVPA) at baseline alongside clinical measurements and fasting blood samples to determine cholesterol, triglycerides, HOMA-IR, and glucose. Isotemporal substitution modeling was performed to determine the potential impact of reallocating 30 min of sedentary time accumulated in a single bout (long bout) with 30 min of interrupted sedentary time, LPA, or MVPA. RESULTS: Sedentary time accounted for 65% of the waking day, of which 45% was accumulated in prolonged (≥30 min) bouts. Reallocation of 30 min of long-bout sedentary time with 30 min of short-bout sedentary time was associated with lower body mass index (BMI) (adjusted β, -0.60; 95% confidence interval [CI], -1.00, -0.21) and waist circumference (WC) (adjusted β, -1.16; 95% CI, -2.08, -0.25). Stronger effects were seen for LPA and MVPA. Reallocation of 30 min of long-bout sedentary time with LPA was associated with higher HDL-cholesterol (adjusted β, 0.02; 95% CI, 0.00-0.03 mmol·L). CONCLUSIONS: Encouraging adults with newly diagnosed type 2 diabetes to break up prolonged periods of sedentary time may be an effective strategy for improving body composition and metabolic health. | en_GB |
dc.description.sponsorship | National Institute for Health Research (NIHR) | en_GB |
dc.identifier.citation | Vol. 47 (10), pp. 2070 - 2075 | en_GB |
dc.identifier.doi | 10.1249/MSS.0000000000000651 | |
dc.identifier.grantnumber | Bristol Nutrition Biomedical Research Unit based at University Hospitals Bristol NHS Foundation Trust and the University of Bristol | en_GB |
dc.identifier.uri | http://hdl.handle.net/10871/35641 | |
dc.language.iso | en | en_GB |
dc.publisher | Lippincott, Williams & Wilkins | en_GB |
dc.relation.url | https://www.ncbi.nlm.nih.gov/pubmed/26378943 | en_GB |
dc.rights | This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. | en_GB |
dc.subject | Accelerometry | en_GB |
dc.subject | Aged | en_GB |
dc.subject | Blood Glucose | en_GB |
dc.subject | Body Mass Index | en_GB |
dc.subject | Cholesterol, HDL | en_GB |
dc.subject | Cross-Sectional Studies | en_GB |
dc.subject | Diabetes Mellitus, Type 2 | en_GB |
dc.subject | Humans | en_GB |
dc.subject | Insulin | en_GB |
dc.subject | Insulin Resistance | en_GB |
dc.subject | Middle Aged | en_GB |
dc.subject | Motor Activity | en_GB |
dc.subject | Sedentary Lifestyle | en_GB |
dc.subject | Triglycerides | en_GB |
dc.subject | Waist Circumference | en_GB |
dc.title | The Potential Impact of Displacing Sedentary Time in Adults with Type 2 Diabetes. | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2019-01-30T11:31:04Z | |
dc.identifier.issn | 1044-3983 | |
exeter.place-of-publication | United States | en_GB |
dc.description | This is the final published version. Available from Lippincott, Williams & Wilkins via the DOI in this record. | en_GB |
dc.identifier.journal | Medicine and Science in Sports and Exercise | en_GB |
dc.rights.uri | https://creativecommons.org/licenses/by/3.0/ | en_GB |
dcterms.dateAccepted | 2015-02-01 | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2015-02-01 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2019-01-30T11:28:17Z | |
refterms.versionFCD | VoR | |
refterms.dateFOA | 2019-01-30T11:31:07Z |
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cited. The work cannot be changed in any way or used commercially.