Neuromuscular Electrical Stimulation as a Potential Countermeasure for Skeletal Muscle Atrophy and Weakness During Human Spaceflight
dc.contributor.author | Maffiuletti, NA | |
dc.contributor.author | Green, DA | |
dc.contributor.author | Vaz, MA | |
dc.contributor.author | Dirks, ML | |
dc.date.accessioned | 2019-09-02T10:24:49Z | |
dc.date.issued | 2019-08-13 | |
dc.description.abstract | Human spaceflight is associated with a substantial loss of skeletal muscle mass and muscle strength. Neuromuscular electrical stimulation (NMES) evokes involuntary muscle contractions, which have the potential to preserve or restore skeletal muscle mass and neuromuscular function during and/or post spaceflight. This assumption is largely based on evidence from terrestrial disuse/immobilization studies without the use of large exercise equipment that may not be available in spaceflight beyond the International Space Station. In this mini-review we provide an overview of the rationale and evidence for NMES based on the terrestrial state-of-the-art knowledge, compare this to that used in orbit, and in ground-based analogs in order to provide practical recommendations for implementation of NMES in future space missions. Emphasis will be placed on knee extensor and plantar flexor muscles known to be particularly susceptible to deconditioning in space missions. | en_GB |
dc.identifier.citation | Vol. 10, article 1031 | en_GB |
dc.identifier.doi | 10.3389/fphys.2019.01031 | |
dc.identifier.uri | http://hdl.handle.net/10871/38511 | |
dc.language.iso | en | en_GB |
dc.publisher | Frontiers Media | en_GB |
dc.rights | © 2019 Maffiuletti, Green, Vaz and Dirks. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. | en_GB |
dc.subject | muscle atrophy | en_GB |
dc.subject | spaceflight analog | en_GB |
dc.subject | countermeasure | en_GB |
dc.subject | muscle weakness | en_GB |
dc.subject | electrical stimulation | en_GB |
dc.title | Neuromuscular Electrical Stimulation as a Potential Countermeasure for Skeletal Muscle Atrophy and Weakness During Human Spaceflight | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2019-09-02T10:24:49Z | |
dc.identifier.issn | 1664-042X | |
exeter.article-number | ARTN 1031 | en_GB |
dc.description | This is the final version. Available on open access from Frontiers Media via the DOI in this record | en_GB |
dc.identifier.journal | Frontiers in Physiology | en_GB |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_GB |
dcterms.dateAccepted | 2019-07-26 | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2019-08-13 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2019-09-02T10:23:14Z | |
refterms.versionFCD | VoR | |
refterms.dateFOA | 2019-09-02T10:24:52Z | |
refterms.panel | C | en_GB |
Files in this item
This item appears in the following Collection(s)
Except where otherwise noted, this item's licence is described as © 2019 Maffiuletti, Green, Vaz and Dirks. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.