dc.contributor.author | Moeller, SB | |
dc.contributor.author | Austin, SF | |
dc.contributor.author | Hvenegaard, M | |
dc.contributor.author | Kistrup, M | |
dc.contributor.author | Gran, S | |
dc.contributor.author | Watkins, E | |
dc.date.accessioned | 2020-02-19T15:08:27Z | |
dc.date.issued | 2019-10-18 | |
dc.description.abstract | Background:One-third of patients with depression do not respond satisfactorily to treatment, and approximately 20% of all patients treated for depression develop a chronic depression. One approach to more effective treatment of chronic and treatment-resistant depression is to target rumination - an underlying mechanism implicated in the development and maintenance of depression.Aim:The purpose of this uncontrolled group study was to investigate the feasibility of individual rumination-focused cognitive behavioural therapy (RfCBT) for patients with chronic and treatment-resistant depression.Method:A total of 10 patients with chronic and treatment-resistant depression were offered 12-16 individual sessions of RfCBT. The primary outcome was depressive symptoms as measured by Hamilton Depression Scale at pre-, post- and 3-month follow-up. Secondary symptoms measured included self-reported rumination and worry.Results:There was a significant reduction in depressive symptoms (p < 0.05), rumination (p < 0.01) and worry (p < 0.5) from pre- to post-treatment. Half of the participants (n = 5) showed significant reliable change on levels of depressive symptoms post-treatment. The reduction in depressive symptoms, rumination and worry were maintained at follow-up.Conclusions:RfCBT was associated with significant reductions in depressive symptoms in a small sample with chronic and treatment-resistant depression. Despite limitations of being a small uncontrolled study with limited follow-up, these results are promising in a difficult to treat population. RfCBT warrants further systematic evaluation. | en_GB |
dc.identifier.citation | Published online 18-October-2019 | en_GB |
dc.identifier.doi | 10.1017/S1352465819000584 | |
dc.identifier.uri | http://hdl.handle.net/10871/40933 | |
dc.language.iso | en | en_GB |
dc.publisher | Cambridge University Press | en_GB |
dc.rights | © British Association for Behavioural and Cognitive Psychotherapies 2019 | en_GB |
dc.subject | chronic treatment-resistant depression | en_GB |
dc.subject | rumination | en_GB |
dc.subject | rumination-focused cognitive behaviour therapy | en_GB |
dc.subject | uncontrolled group study | en_GB |
dc.subject | worry | en_GB |
dc.title | Rumination-focused cognitive behaviour therapy for non-responsive chronic depression: An uncontrolled group study | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2020-02-19T15:08:27Z | |
dc.identifier.issn | 1352-4658 | |
dc.description | This is the final version. Available from CUP via the DOI in this record. | en_GB |
dc.identifier.journal | Behavioural and Cognitive Psychotherapy | en_GB |
dc.rights.uri | http://www.rioxx.net/licenses/all-rights-reserved | en_GB |
dcterms.dateAccepted | 2019-09-02 | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2019-09-02 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2020-02-19T15:05:12Z | |
refterms.versionFCD | VoR | |
refterms.dateFOA | 2020-02-19T15:08:47Z | |
refterms.panel | A | en_GB |