Theta burst stimulation dissociates attention and action updating in human inferior frontal cortex.
Aron, Adam R.
Stevens, Michaël A.
Chambers, Christopher D.
Proceedings of the National Academy of Sciences of the United States of America
The National Academy of Sciences
Everyday circumstances require efficient updating of behavior. Brain systems in the right inferior frontal cortex have been identified as critical for some aspects of behavioral updating, such as stopping actions. However, the precise role of these neural systems is controversial. Here we examined how the inferior frontal cortex updates behavior by combining reversible cortical interference (transcranial magnetic stimulation) with an experimental task that measures different types of updating. We found that the right inferior frontal cortex can be functionally segregated into two subregions: a dorsal region, which is critical for visual detection of changes in the environment, and a ventral region, which updates the corresponding action plan. This dissociation reconciles competing accounts of prefrontal organization and casts light on the neural architecture of human cognitive control.
This is a postprint of an article published in Proceedings of the National Academy of Sciences of the United States of America. Copyright © 2010, The National Academy of Sciences. Available online at: http://www.pnas.org/
Proceedings of the National Academy of Sciences of the United States of America, 2010, Vol. 107, Issue 31, pp. 13966 - 13971
Place of publication