Endothelial markers in malignant vascular tumours of the liver: superiority of QB-END/10 over von Willebrand factor and Ulex europaeus agglutinin 1.

DSpace/Manakin Repository

Open Research Exeter (ORE)

Endothelial markers in malignant vascular tumours of the liver: superiority of QB-END/10 over von Willebrand factor and Ulex europaeus agglutinin 1.

Please use this identifier to cite or link to this item: http://hdl.handle.net/10036/12005

Share:                 



Title: Endothelial markers in malignant vascular tumours of the liver: superiority of QB-END/10 over von Willebrand factor and Ulex europaeus agglutinin 1.
Author: Anthony, P P
Ramani, P
Citation: Journal of Clinical Pathology, 1991, 44(1):29-32
Journal: Journal of Clinical Pathology
Date Issued: 1991-01
URI: http://hdl.handle.net/10036/12005
Abstract: A new monoclonal antibody, QB-END/10, raised against the CD34 antigen in human endothelial cell membranes and haemopoietic progenitor cells, was studied for its usefulness as a marker of neoplastic vascular cells in 21 angiosarcomas and seven malignant haemangioendotheliomas of the liver. QB-END/10 was both more sensitive and more specific than Von Willebrand factor (VWF) and Ulex europaeus 1 agglutinin (UEA-1) in labelling endothelial cells and it did not cross react with epithelia as UEA-1 often does. Staining was uniformly strong and clear in all histological variants of these two tumours. QB-END/10 should prove particularly useful in the differential diagnosis of malignant vascular tumours of the liver.
Type: Article
ISSN: 0021-97461472-4146
PubMed ID: 1705261
PubMed Central ID: 497010


Please note: Before reusing this item please check the rights under which it has been made available. Some items are restricted to non-commercial use. Please cite the published version where applicable.

Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Browse

My Account

Local Links