Endothelial markers in malignant vascular tumours of the liver: superiority of QB-END/10 over von Willebrand factor and Ulex europaeus agglutinin 1.

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Endothelial markers in malignant vascular tumours of the liver: superiority of QB-END/10 over von Willebrand factor and Ulex europaeus agglutinin 1.

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dc.contributor.author Anthony, P P en_GB
dc.contributor.author Ramani, P en_GB
dc.date.accessioned 2007-05-21T14:45:15Z en_GB
dc.date.accessioned 2011-01-25T10:08:09Z en_US
dc.date.accessioned 2013-03-20T17:08:11Z
dc.date.issued 1991-01 en_GB
dc.description.abstract A new monoclonal antibody, QB-END/10, raised against the CD34 antigen in human endothelial cell membranes and haemopoietic progenitor cells, was studied for its usefulness as a marker of neoplastic vascular cells in 21 angiosarcomas and seven malignant haemangioendotheliomas of the liver. QB-END/10 was both more sensitive and more specific than Von Willebrand factor (VWF) and Ulex europaeus 1 agglutinin (UEA-1) in labelling endothelial cells and it did not cross react with epithelia as UEA-1 often does. Staining was uniformly strong and clear in all histological variants of these two tumours. QB-END/10 should prove particularly useful in the differential diagnosis of malignant vascular tumours of the liver. en_GB
dc.identifier.citation Journal of Clinical Pathology, 1991, 44(1):29-32 en_GB
dc.identifier.uri http://hdl.handle.net/10036/12005 en_GB
dc.language.iso en_US en_GB
dc.title Endothelial markers in malignant vascular tumours of the liver: superiority of QB-END/10 over von Willebrand factor and Ulex europaeus agglutinin 1. en_GB
dc.type Article en_GB
dc.date.available 1991-01 en_GB
dc.date.available 2007-05-21T14:45:15Z en_GB
dc.date.available 2011-01-25T10:08:09Z en_US
dc.date.available 2013-03-20T17:08:11Z
dc.identifier.issn 0021-9746 en_GB
dc.identifier.issn 1472-4146 en_GB
dc.format.dig YES en_GB
dc.identifier.journal Journal of Clinical Pathology en_GB
dc.identifier.pmcid 497010 en_GB
dc.identifier.pmid 1705261 en_GB


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