Institute of Medical Education: Recent submissions
Now showing items 201-205 of 299
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Cloning, expression, and characterization of a cold-adapted lipase gene from an antarctic deep-sea psychorotrophic bacterium, Psychobacter sp. 7195
(Korean Society for Microbiology and Biotechnology, 1 April 2007)A psychrotrophic strain 7195 showing extracellular lipolytic activity towards tributyrin was isolated from deep-sea sediment of Prydz Bay and identified as a Psychrobacter species. By screening a genomic DNA library of ... -
Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity
(Oxford University Press, 12 October 2012)Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most frequent known cause of late-onset Parkinson's disease (PD). To explore the therapeutic potential of small molecules targeting the LRRK2 kinase domain, we ... -
Mutations in Chromatin Modifier and Ephrin Signaling Genes in Vein of Galen Malformation
(Elsevier (Cell Press), 18 December 2018)Normal vascular development includes the formation and specification of arteries, veins, and intervening capillaries. Vein of Galen malformations (VOGMs) are among the most common and severe neonatal brain arterio-venous ... -
Imaging and opportunistic identification of fractures
(Pavilion Publishing, 30 November 2018)Osteoporosis is characterised by low bone mineral density and micro-architectural deterioration of bone leading to an increased risk of low trauma fractures, associated morbidity and mortality. This article describes the ... -
Cervical spine fractures in the elderly: are there missed opportunities for prevention?
(Springer, 7 November 2018)Background: The most common site of cervical spine fracture in the elderly is the odontoid process. These fractures result predominantly from ground level falls. Osteoporosis has been identified as an important predisposing ...