Institute of Medical Education: Recent submissions
Now showing items 81-85 of 299
-
New drugs on the horizon for cerebral edema: what’s in the clinical development pipeline?
(Taylor & Francis, 20 August 2020)Introduction: Research has advanced our understanding of the molecular and cellular mechanisms of cerebral edema and has propelled the development of novel antiedema therapeutics. Current evidence supports aberrant neuro-glial ... -
Smoothened receptor signaling regulates the developmental shift of GABA polarity in rat somatosensory cortex.
(The Company of Biologists, 28 September 2020)Sonic Hedgehog (Shh) and its patched-smoothened receptor complex control a variety of functions in the developing central nervous system such as neural cell proliferation and differentiation. Recently, Shh signaling ... -
Outcome of hospitalization for COVID-19 in patients with interstitial lung disease: an international multicenter study
(American Thoracic Society, 2 October 2020)Rationale: The impact of COVID-19 on patients with Interstitial Lung Disease (ILD) has not been established. Objectives: To assess outcomes in patients with ILD hospitalized for COVID-19 versus those without ILD in a ... -
Extracellular ATP increases glucose metabolism in skeletal muscle cells in a P2 receptor dependent manner but does not contribute to palmitate-induced insulin resistance
(Frontiers Media, 25 September 2020)Saturated fatty acids such as palmitate contribute to the development of Type 2 Diabetes by reducing insulin sensitivity, increasing inflammation and potentially contributing to anabolic resistance. We hypothesized that ... -
Circadian VIPergic Neurons of the Suprachiasmatic Nuclei Sculpt the Sleep-Wake Cycle
(Cell Press, 10 September 2020)Although the mammalian rest-activity cycle is controlled by a "master clock" in the suprachiasmatic nucleus (SCN) of the hypothalamus, it is unclear how firing of individual SCN neurons gates individual features of daily ...