Institute of Medical Education: Recent submissions
Now showing items 96-100 of 299
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Depletion of the phosphatase inhibitor, PPP1R1A, may contribute to beta-cell loss in Type 1 diabetes
(University of Exeter University of Exeter Medical School, 17 August 2020)Increasing evidence implicates a persistent enteroviral infection of β-cells as a potential trigger for the development of Type 1 diabetes (T1D). In support of this, findings presented in this thesis demonstrate that ... -
Cardiac rehabilitation and physical activity levels in heart failure
(University of Exeter College of Medicine and Health, 20 July 2020)Background Maintenance of adequate physical activity (PA) is a key recommendation for people with and without chronic disease, with well-established health benefits. However, there is uncertainty in the level of objectively ... -
What works in violence prevention among young people?: a systematic review of reviews
(SAGE Publications, 17 July 2020)Violence prevention programs aim to raise awareness, change attitudes, normative beliefs, motivation, and behavioral responses. Many programs have been developed and evaluated, and optimistic claims about effectiveness ... -
Defining the genetic and molecular basis of inherited eye diseases present in Pakistan
(University of Exeter College of Medicine and Health, 13 July 2020)Human Mendelian genetics aims to define the link between the phenotypical manifestations of a disease, and the identity of the gene that when mutated causes disease. Rare ocular genetic disorders are typically difficult ... -
Investigation into Human Erythrocyte Peroxiredoxin 2 : S-Nitrosation and Interaction with Haemoglobin
(University of Exeter University of Exeter Medical School, 9 December 2019)The most abundant intracellular protein in erythrocytes is haemoglobin (Hb) and the third most abundant protein is peroxiredoxin 2 (Prx2). Prx2 exists in both dimeric and decameric form; its dimeric form has two cysteines ...