Institute of Medical Education: Recent submissions
Now showing items 91-95 of 299
-
The role of molecular genetics in the clinical management of sporadic medullary thyroid carcinoma: A systematic review
(Wiley / Society for Endocrinology, 13 July 2019)Background: The significant variation in the clinical behaviour of sporadic medullary thyroid carcinoma (sMTC) causes uncertainty when planning the management of these patients. Several tumour genetic and epigenetic markers ... -
Does Obesity Cause Thyroid Cancer? A Mendelian Randomization Study
(Endocrine Society / Oxford University Press, 11 May 2020)BACKGROUND: The incidence of thyroid cancer is rising, and relatively little is known about modifiable risk factors for the condition. Observational studies have suggested a link between adiposity and thyroid cancer; ... -
Defining new molecules and biological pathways underlying neurodegenerative disease
(University of Exeter College of Medicine and Health, 1 September 2020)Motor neurone diseases (MNDs) are a group of disorders characterised by the degeneration of upper and/or lower motor neurones. Unlike communicable diseases in which frequency is decreasing due to improved healthcare ... -
Assessing performance of pathogenicity predictors using clinically relevant variant datasets
(BMJ Publishing Group, 25 August 2020)Background Pathogenicity predictors are integral to genomic variant interpretation but, despite their widespread usage, an independent validation of performance using a clinically relevant dataset has not been undertaken ... -
What medical imaging professionals talk about when they talk about compassion
(Elsevier / Canadian Association of Medical Radiation Technology, 25 August 2020)Background Compassion is a poorly understood concept in Medical Imaging research, but an increase in its focus was recommended in the Francis Report (2013). Little research has been conducted in this area to date. Methods The ...