Faculty of Health and Life Sciences: Recent submissions
Now showing items 6-10 of 1497
-
DNAm scores for serum GDF15 and NT-proBNP levels associate with a range of traits affecting the body and brain
(BMC, 10 September 2024)Background: Plasma growth differentiation factor 15 (GDF15) and N‐terminal proB‐type natriuretic peptide (NT‐proBNP) are cardiovascular biomarkers that associate with a range of diseases. Epigenetic scores (EpiScores) for ... -
Blood-based epigenome-wide analyses of chronic low-grade inflammation across diverse population cohorts
(Cell Press, 30 April 2024)Chronic inflammation is a hallmark of age-related disease states. The effectiveness of inflammatory proteins including C-reactive protein (CRP) in assessing long-term inflammation is hindered by their phasic nature. DNA ... -
Epigenetic contributions to clinical risk prediction of cardiovascular disease
(Wolters Kluwer / American Heart Association, 30 January 2024)BACKGROUND: Cardiovascular disease (CVD) is among the leading causes of death worldwide. The discovery of new omics biomarkers could help to improve risk stratification algorithms and expand our understanding of molecular ... -
A homozygous TARS2 variant is a novel cause of syndromic neonatal diabetes
(Wiley / Diabetes UK, 7 November 2024)Aims: Neonatal diabetes is a monogenic condition which can be the presenting feature of complex syndromes. The aim of this study was to identify novel genetic causes of neonatal diabetes with neurological features including ...