Ventral striatum activity in response to reward: differences between bipolar I and II disorders.
Caseras, X; Lawrence, Natalia; Murphy, K; et al.Wise, RG; Phillips, ML
Date: 1 May 2013
Journal
American Journal of Psychiatry
Publisher
American Psychiatric Publishing
Publisher DOI
Related links
Abstract
Little is known about the neurobiology of bipolar II disorder. While bipolar I disorder is associated with abnormally elevated activity in response to reward in the ventral striatum, a key component of reward circuitry, no studies have compared reward circuitry function in bipolar I and bipolar II disorders. Furthermore, associations ...
Little is known about the neurobiology of bipolar II disorder. While bipolar I disorder is associated with abnormally elevated activity in response to reward in the ventral striatum, a key component of reward circuitry, no studies have compared reward circuitry function in bipolar I and bipolar II disorders. Furthermore, associations among reward circuitry activity, reward sensitivity, and striatal volume remain underexplored in bipolar and healthy individuals. The authors examined reward activity in the ventral striatum in participants with bipolar I and II disorders and healthy individuals, the relationships between ventral striatal activity and reward sensitivity across all participants, and between-group differences in striatal gray matter volume and relationships with ventral striatal activity across all participants.
Psychology - old structure
Collections of Former Colleges
Item views 0
Full item downloads 0