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dc.contributor.authorCaseras, X
dc.contributor.authorLawrence, Natalia
dc.contributor.authorMurphy, K
dc.contributor.authorWise, RG
dc.contributor.authorPhillips, ML
dc.date.accessioned2013-07-01T09:08:13Z
dc.date.issued2013-05-01
dc.description.abstractLittle is known about the neurobiology of bipolar II disorder. While bipolar I disorder is associated with abnormally elevated activity in response to reward in the ventral striatum, a key component of reward circuitry, no studies have compared reward circuitry function in bipolar I and bipolar II disorders. Furthermore, associations among reward circuitry activity, reward sensitivity, and striatal volume remain underexplored in bipolar and healthy individuals. The authors examined reward activity in the ventral striatum in participants with bipolar I and II disorders and healthy individuals, the relationships between ventral striatal activity and reward sensitivity across all participants, and between-group differences in striatal gray matter volume and relationships with ventral striatal activity across all participants.en_GB
dc.identifier.citationAmerican Journal of Psychiatry, 2013, Vol. 170, Issue 5, pp. 533 - 541en_GB
dc.identifier.doi10.1176/appi.ajp.2012.12020169
dc.identifier.other1676088
dc.identifier.urihttp://hdl.handle.net/10871/11463
dc.language.isoenen_GB
dc.publisherAmerican Psychiatric Publishingen_GB
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/23558337en_GB
dc.relation.urlhttp://ajp.psychiatryonline.org/article.aspx?articleid=1676088en_GB
dc.titleVentral striatum activity in response to reward: differences between bipolar I and II disorders.en_GB
dc.typeArticleen_GB
dc.date.available2013-07-01T09:08:13Z
exeter.place-of-publicationUnited States
dc.descriptionaddresses: MRC Center for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University, UK. caserasx@cardiff.ac.uken_GB
dc.descriptionnotes: PMCID: PMC3640293en_GB
dc.descriptiontypes: Journal Article; Research Support, Non-U.S. Gov'ten_GB
dc.descriptionThis is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/3.0/ and http://creativecommons.org/licenses/by-nc/3.0/legalcode.en_GB
dc.descriptionCopyright © 2013 by the American Psychiatric Associationen_GB
dc.descriptionThe official published article is available online at http://ajp.psychiatryonline.org/article.aspx?articleid=1676088en_GB
dc.identifier.journalAmerican Journal of Psychiatryen_GB


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