Artificial selection reveals the role of transcriptional constraints in the maintenance of life history variation
dc.contributor.author | Pick, JL | |
dc.contributor.author | Hatakeyama, M | |
dc.contributor.author | Ihle, KE | |
dc.contributor.author | Gasparini, J | |
dc.contributor.author | Haussy, C | |
dc.contributor.author | Ishishita, S | |
dc.contributor.author | Matsuda, Y | |
dc.contributor.author | Yoshimura, T | |
dc.contributor.author | Kanaoka, MM | |
dc.contributor.author | Shimizu-Inatsugi, R | |
dc.contributor.author | Shimizu, KK | |
dc.contributor.author | Tschirren, B | |
dc.date.accessioned | 2020-04-16T08:37:01Z | |
dc.date.issued | 2020-04-07 | |
dc.description.abstract | The trade‐off between reproduction and self‐maintenance is a cornerstone of life history theory, yet its proximate underpinnings are elusive. Here, we used an artificial selection approach to create replicated lines of Japanese quail (Coturnix japonica) that differ genetically in their reproductive investment. Whole transcriptome sequencing revealed that females from lines selected for high reproductive output show a consistent upregulation of genes associated with reproduction but a simultaneous downregulation of immune genes. Concordant phenotypic differences in immune function (i.e., specific antibody response against keyhole limpet hemocyanin) were observed between the selection lines, even in males who do not provide parental care. Our findings demonstrate the key role of obligate transcriptional constraints in the maintenance of life history variation. These constraints set fundamental limits to productivity and health in natural and domestic animal populations. | en_GB |
dc.description.sponsorship | Universität Zürich | en_GB |
dc.description.sponsorship | KAKENHI | en_GB |
dc.description.sponsorship | Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung | en_GB |
dc.identifier.citation | Published online 7 April 2020 | en_GB |
dc.identifier.doi | 10.1002/evl3.166 | |
dc.identifier.grantnumber | 23113004 | en_GB |
dc.identifier.grantnumber | 24113510 | en_GB |
dc.identifier.grantnumber | 26113709 | en_GB |
dc.identifier.grantnumber | P2ZHP3_164962 | en_GB |
dc.identifier.grantnumber | PP00P3_128386 | en_GB |
dc.identifier.grantnumber | PP00P3_157455 | en_GB |
dc.identifier.grantnumber | 31003A_159767 | en_GB |
dc.identifier.uri | http://hdl.handle.net/10871/120664 | |
dc.language.iso | en | en_GB |
dc.publisher | Wiley | en_GB |
dc.rights | © 2020 The Authors. Evolution Letters published by Wiley Periodicals, Inc. on behalf of Society for the Study of Evolution (SSE) and European Society for Evolutionary Biology (ESEB). This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. | en_GB |
dc.subject | Costs of reproduction | en_GB |
dc.subject | egg size | en_GB |
dc.subject | immune defence | en_GB |
dc.subject | life‐history trade‐offs | en_GB |
dc.subject | maternal care | en_GB |
dc.subject | natural selection | en_GB |
dc.title | Artificial selection reveals the role of transcriptional constraints in the maintenance of life history variation | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2020-04-16T08:37:01Z | |
dc.identifier.issn | 2056-3744 | |
dc.description | This is the final version. Available on open access from Wiley via the DOI in this record | en_GB |
dc.identifier.journal | Evolution Letters | en_GB |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_GB |
dcterms.dateAccepted | 2020-02-18 | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2020-02-18 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2020-04-14T11:05:42Z | |
refterms.versionFCD | VoR | |
refterms.dateFOA | 2020-04-16T08:37:06Z | |
refterms.panel | A | en_GB |
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Except where otherwise noted, this item's licence is described as © 2020 The Authors. Evolution Letters published by Wiley Periodicals, Inc. on behalf of Society for the Study of Evolution (SSE) and European Society for Evolutionary Biology (ESEB).
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.