A novel Ca2+ signaling pathway coordinates environmental phosphorus sensing and nitrogen metabolism in marine diatoms
dc.contributor.author | Helliwell, KE | |
dc.contributor.author | Harrison, EL | |
dc.contributor.author | Christie-Oleza, JA | |
dc.contributor.author | Rees, AP | |
dc.contributor.author | Kleiner, FH | |
dc.contributor.author | Gaikwad, T | |
dc.contributor.author | Downe, J | |
dc.contributor.author | Aguilo-Ferretjans, MM | |
dc.contributor.author | Al-Moosawi, L | |
dc.contributor.author | Brownlee, C | |
dc.contributor.author | Wheeler, GL | |
dc.date.accessioned | 2021-01-27T15:16:11Z | |
dc.date.issued | 2020-12-28 | |
dc.description.abstract | Diatoms are a diverse and globally important phytoplankton group, responsible for an estimated 20% of carbon fixation on Earth. They frequently form spatially extensive phytoplankton blooms, responding rapidly to increased availability of nutrients, including phosphorus (P) and nitrogen (N). Although it is well established that diatoms are common first responders to nutrient influxes in aquatic ecosystems, little is known of the sensory mechanisms that they employ for nutrient perception. Here, we show that P-limited diatoms use a Ca2+-dependent signaling pathway, not previously described in eukaryotes, to sense and respond to the critical macronutrient P. We demonstrate that P-Ca2+ signaling is conserved between a representative pennate (Phaeodactylum tricornutum) and centric (Thalassiosira pseudonana) diatom. Moreover, this pathway is ecologically relevant, being sensitive to sub-micromolar concentrations of inorganic phosphate and a range of environmentally abundant P forms. Notably, we show that diatom recovery from P limitation requires rapid and substantial increases in N assimilation and demonstrate that this process is dependent on P-Ca2+ signaling. P-Ca2+ signaling thus governs the capacity of diatoms to rapidly sense and respond to P resupply, mediating fundamental cross-talk between the vital nutrients P and N and maximizing diatom resource competition in regions of pulsed nutrient supply. | en_GB |
dc.description.sponsorship | NERC-IRF | en_GB |
dc.identifier.citation | Published online December 28 2020 | en_GB |
dc.identifier.doi | 10.1016/j.cub.2020.11.073 | |
dc.identifier.grantnumber | NE/R015449/2 | en_GB |
dc.identifier.uri | http://hdl.handle.net/10871/124525 | |
dc.language.iso | en | en_GB |
dc.publisher | Elsevier | en_GB |
dc.rights | © 2020 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/) | en_GB |
dc.subject | diatoms | en_GB |
dc.subject | Ca2+ signaling | en_GB |
dc.subject | nutrient sensing | en_GB |
dc.subject | phosphate | en_GB |
dc.subject | Phaeodactylum | en_GB |
dc.subject | Thalassiosira | en_GB |
dc.subject | algal bloom | en_GB |
dc.subject | nitrate | en_GB |
dc.subject | resource competition | en_GB |
dc.subject | proteomics | en_GB |
dc.title | A novel Ca2+ signaling pathway coordinates environmental phosphorus sensing and nitrogen metabolism in marine diatoms | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2021-01-27T15:16:11Z | |
dc.identifier.issn | 0960-9822 | |
dc.description | This is the final version. Available from Elsevier via the DOI in this record. | en_GB |
dc.description | The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE65 partner repository with the dataset identifier PRIDE: PXD022586 | en_GB |
dc.identifier.eissn | 1879-0445 | |
dc.identifier.journal | Current Biology | en_GB |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en_GB |
dcterms.dateAccepted | 2020-11-30 | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2020-12-28 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2021-01-27T15:08:20Z | |
refterms.versionFCD | VoR | |
refterms.dateFOA | 2021-01-27T15:16:19Z | |
refterms.panel | A | en_GB |
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This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)