Effectiveness of collaborative care in reducing suicidal ideation: An individual participant data meta-analysis
dc.contributor.author | Grigoroglou, C | |
dc.contributor.author | van der Feltz-Cornelis, C | |
dc.contributor.author | Hodkinson, A | |
dc.contributor.author | Coventry, PA | |
dc.contributor.author | Zghebi, SS | |
dc.contributor.author | Kontopantelis, E | |
dc.contributor.author | Bower, P | |
dc.contributor.author | Lovell, K | |
dc.contributor.author | Gilbody, S | |
dc.contributor.author | Waheed, W | |
dc.contributor.author | Dickens, C | |
dc.contributor.author | Archer, J | |
dc.contributor.author | Blakemore, A | |
dc.contributor.author | Adler, DA | |
dc.contributor.author | Aragones, E | |
dc.contributor.author | Björkelund, C | |
dc.contributor.author | Bruce, ML | |
dc.contributor.author | Buszewicz, M | |
dc.contributor.author | Carney, RM | |
dc.contributor.author | Cole, MG | |
dc.contributor.author | Davidson, KW | |
dc.contributor.author | Gensichen, J | |
dc.contributor.author | Grote, NK | |
dc.contributor.author | Russo, J | |
dc.contributor.author | Huijbregts, K | |
dc.contributor.author | Huffman, JC | |
dc.contributor.author | Menchetti, M | |
dc.contributor.author | Patel, V | |
dc.contributor.author | Richards, DA | |
dc.contributor.author | Rollman, B | |
dc.contributor.author | Smit, A | |
dc.contributor.author | Zijlstra-Vlasveld, MC | |
dc.contributor.author | Wells, KB | |
dc.contributor.author | Zimmermann, T | |
dc.contributor.author | Unutzer, J | |
dc.contributor.author | Panagioti, M | |
dc.date.accessioned | 2021-05-05T09:55:48Z | |
dc.date.issued | 2021-04-21 | |
dc.description.abstract | To assess whether CC is more effective at reducing suicidal ideation in people with depression compared with usual care, and whether study and patient factors moderate treatment effects. METHOD: We searched Medline, Embase, PubMed, PsycINFO, CINAHL, CENTRAL from inception to March 2020 for Randomised Controlled Trials (RCTs) that compared the effectiveness of CC with usual care in depressed adults, and reported changes in suicidal ideation at 4 to 6 months post-randomisation. Mixed-effects models accounted for clustering of participants within trials and heterogeneity across trials. This study is registered with PROSPERO, CRD42020201747. RESULTS: We extracted data from 28 RCTs (11,165 patients) of 83 eligible studies. We observed a small significant clinical improvement of CC on suicidal ideation, compared with usual care (SMD, -0.11 [95%CI, -0.15 to -0.08]; I2, 0·47% [95%CI 0.04% to 4.90%]). CC interventions with a recognised psychological treatment were associated with small reductions in suicidal ideation (SMD, -0.15 [95%CI -0.19 to -0.11]). CC was more effective for reducing suicidal ideation among patients aged over 65 years (SMD, - 0.18 [95%CI -0.25 to -0.11]). CONCLUSION: Primary care based CC with an embedded psychological intervention is the most effective CC framework for reducing suicidal ideation and older patients may benefit the most. | en_GB |
dc.description.sponsorship | Medical Research Council (MRC) | en_GB |
dc.description.sponsorship | National Institute for Health Research (NIHR) | en_GB |
dc.identifier.citation | Vol. 71, pp. 27 - 35 | en_GB |
dc.identifier.doi | 10.1016/j.genhosppsych.2021.04.004 | |
dc.identifier.grantnumber | G0701013 | en_GB |
dc.identifier.uri | http://hdl.handle.net/10871/125548 | |
dc.language.iso | en | en_GB |
dc.publisher | Elsevier | en_GB |
dc.relation.url | https://www.ncbi.nlm.nih.gov/pubmed/33915444 | en_GB |
dc.rights | © 2021 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). | en_GB |
dc.title | Effectiveness of collaborative care in reducing suicidal ideation: An individual participant data meta-analysis | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2021-05-05T09:55:48Z | |
dc.identifier.issn | 0163-8343 | |
exeter.place-of-publication | United States | en_GB |
dc.description | This is the final version. Available on open access from Elsevier via the DOI in this record | en_GB |
dc.description | Data sharing: Data are available upon request from the corresponding author. | en_GB |
dc.identifier.journal | General Hospital Psychiatry | en_GB |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_GB |
dcterms.dateAccepted | 2021-04-18 | |
exeter.funder | ::Medical Research Council (MRC) | en_GB |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2021-04-21 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2021-05-05T09:53:52Z | |
refterms.versionFCD | VoR | |
refterms.dateFOA | 2021-05-05T09:56:38Z | |
refterms.panel | A | en_GB |
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Except where otherwise noted, this item's licence is described as © 2021 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).