dc.contributor.author | Fitzpatrick, N | |
dc.contributor.author | Chachay, V | |
dc.contributor.author | Bowtell, J | |
dc.contributor.author | Jackman, S | |
dc.contributor.author | Capra, S | |
dc.contributor.author | Shore, A | |
dc.contributor.author | Briskey, D | |
dc.date.accessioned | 2021-05-10T13:18:03Z | |
dc.date.issued | 2021-08-02 | |
dc.description.abstract | Lutein and zeaxanthin (L/Z), xanthophylls obtained from the diet, are deposited in
the macula of the eye. The macular concentration of L/Z is quantifiable as macular pigment
optical density (MPOD). The aim of this review was to critically appraise the effect on MPOD
of increasing L/Z intake by dietary intervention in adults. Pubmed, Cochrane Library, Web of
Science, and Cinahl were searched up to April 2020. Ten studies investigating populations with
and without age-related macular degeneration were included. MPOD increased significantly in
two of the eight controlled studies. Studies varied largely in the prescribed dietary L/Z dosage,
duration, and participant characteristics. No relationships between types of dietary L/Z
interventions and MPOD response could be determined. Limited monitoring of habitual dietary
L/Z intake was identified as a major limitation of all ten studies. Habitual dietary L/Z intake
should be closely monitored in future studies to account for their effects on MPOD response
to dietary L/Z interventions. | en_GB |
dc.description.sponsorship | Australian Government Research Training Program (RTP) | en_GB |
dc.identifier.citation | Published online 2 August 2021 | |
dc.identifier.doi | 10.1093/nutrit/nuab038 | |
dc.identifier.uri | http://hdl.handle.net/10871/125602 | |
dc.language.iso | en | en_GB |
dc.publisher | Oxford University Press / International Life Sciences Institute | en_GB |
dc.rights.embargoreason | Under embargo until 2 August 2022 in compliance with publisher policy | en_GB |
dc.rights | © The Author(s) 2021. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. | |
dc.subject | lutein | en_GB |
dc.subject | zeaxanthin | en_GB |
dc.subject | macular pigment optical density | en_GB |
dc.subject | macula | en_GB |
dc.subject | dietary intervention | en_GB |
dc.title | An appraisal of trials investigating the effects on macular pigment optical density of lutein and zeaxanthin dietary interventions: a narrative review | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2021-05-10T13:18:03Z | |
dc.identifier.issn | 0029-6643 | |
dc.description | This is the author accepted manuscript. The final version is available from Oxford University Press via the DOI in this record | en_GB |
dc.identifier.journal | Nutrition Reviews | en_GB |
dc.rights.uri | http://www.rioxx.net/licenses/all-rights-reserved | en_GB |
dcterms.dateAccepted | 2021-04-21 | |
rioxxterms.version | AM | en_GB |
rioxxterms.licenseref.startdate | 2021-04-21 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2021-05-09T23:25:59Z | |
refterms.versionFCD | AM | |
refterms.panel | C | en_GB |