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dc.contributor.authorDelgado, J
dc.contributor.authorEvans, PH
dc.contributor.authorGray, DP
dc.contributor.authorSidaway-Lee, K
dc.contributor.authorAllan, L
dc.contributor.authorClare, L
dc.contributor.authorBallard, C
dc.contributor.authorMasoli, J
dc.contributor.authorValderas, JM
dc.contributor.authorMelzer, D
dc.date.accessioned2022-02-08T15:21:01Z
dc.date.issued2022-01-24
dc.date.updated2022-02-08T14:41:49Z
dc.description.abstractBACKGROUND: Higher continuity of GP care (CGPC), that is, consulting the same doctor consistently, can improve doctor-patient relationships and increase quality of care; however, its effects on patients with dementia are mostly unknown. AIM: To estimate the associations between CGPC and potentially inappropriate prescribing (PIP), and with the incidence of adverse health outcomes (AHOs) in patients with dementia. DESIGN AND SETTING: A retrospective cohort study with 1 year of follow-up anonymised medical records from 9324 patients with dementia, aged ≥65 years living in England in 2016. METHOD: CGPC measures include the Usual Provider of Care (UPC), Bice-Boxerman Continuity of Care (BB), and Sequential Continuity (SECON) indices. Regression models estimated associations with PIPs and survival analysis with incidence of AHOs during the follow-up adjusted for age, sex, deprivation level, 14 comorbidities, and frailty. RESULTS: The highest quartile (HQ) of UPC (highest continuity) had 34.8% less risk of delirium (odds ratio [OR] 0.65, 95% confidence interval [CI] = 0.51 to 0.84), 57.9% less risk of incontinence (OR 0.42, 95% CI = 0.31 to 0.58), and 9.7% less risk of emergency admissions to hospital (OR 0.90, 95% CI = 0.82 to 0.99) compared with the lowest quartile. Polypharmacy and PIP were identified in 81.6% (n = 7612) and 75.4% (n = 7027) of patients, respectively. The HQ had fewer prescribed medications (HQ: mean 8.5, lowest quartile (LQ): mean 9.7, P<0.01) and had fewer PIPs (HQ: mean 2.1, LQ: mean 2.5, P<0.01), including fewer loop diuretics in patients with incontinence, drugs that can cause constipation, and benzodiazepines with high fall risk. The BB and SECON measures produced similar findings. CONCLUSION: Higher CGPC for patients with dementia was associated with safer prescribing and lower rates of major adverse events. Increasing continuity of care for patients with dementia may help improve treatment and outcomes.en_GB
dc.description.sponsorshipAlzheimer’s Societyen_GB
dc.format.extentbjgp.2021.0413-
dc.format.mediumPrint-Electronic
dc.identifier.citationPublished online 27 January 2022en_GB
dc.identifier.doihttps://doi.org/10.3399/BJGP.2021.0413
dc.identifier.grantnumberAS-JF-16b-007en_GB
dc.identifier.urihttp://hdl.handle.net/10871/128735
dc.identifierORCID: 0000-0002-5277-3545 (Evans, Philip H)
dc.identifierScopusID: 55732332800 | 7402236028 (Evans, Philip H)
dc.identifierORCID: 0000-0002-3740-5162 | 0000-0003-3989-5318 (Clare, Linda)
dc.language.isoenen_GB
dc.publisherRoyal College of General Practitionersen_GB
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pubmed/35074796en_GB
dc.rights© The Authors 2021. This article is Open Access: CC BY 4.0 licence (http://creativecommons.org/licences/by/4.0/).en_GB
dc.subjectcomorbidityen_GB
dc.subjectcontinuity of patient careen_GB
dc.subjectdeliriumen_GB
dc.subjectdementiaen_GB
dc.subjectgeneral practiceen_GB
dc.subjectprescribingen_GB
dc.titleContinuity of GP care for patients with dementia: impact on prescribing and the health of patientsen_GB
dc.typeArticleen_GB
dc.date.available2022-02-08T15:21:01Z
dc.identifier.issn0960-1643
exeter.place-of-publicationEngland
dc.descriptionThis is the final version. Available on open access from the Royal College of General Practitioners via the DOI in this recorden_GB
dc.descriptionData availability: For access to study protocol and programming code contact the corresponding author, João Delgado. The raw data are available from Clinical Practice Research Datalink.en_GB
dc.identifier.eissn1478-5242
dc.identifier.journalBritish Journal of General Practiceen_GB
dc.relation.ispartofBr J Gen Pract
dc.rights.urihttps://creativecommons.org/licences/by/4.0/en_GB
dcterms.dateAccepted2021-11-03
rioxxterms.versionVoRen_GB
rioxxterms.licenseref.startdate2022-01-24
rioxxterms.typeJournal Article/Reviewen_GB
refterms.dateFCD2022-02-08T15:18:44Z
refterms.versionFCDVoR
refterms.dateFOA2022-02-08T15:21:08Z
refterms.panelAen_GB
refterms.dateFirstOnline2022-01-24


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© The Authors 2021. This article is Open Access: CC BY 4.0 licence (http://creativecommons.org/licences/by/4.0/).
Except where otherwise noted, this item's licence is described as © The Authors 2021. This article is Open Access: CC BY 4.0 licence (http://creativecommons.org/licences/by/4.0/).