Impact of heterotopic ossifcation following lumbar total disk replacement: a systematic review
| dc.contributor.author | Hood, C | |
| dc.contributor.author | Zamani, R | |
| dc.contributor.author | Akrami, M | |
| dc.date.accessioned | 2022-04-26T13:31:32Z | |
| dc.date.issued | 2022-04-23 | |
| dc.date.updated | 2022-04-26T12:59:47Z | |
| dc.description.abstract | Background context Lumbar total disc replacement (TDR) is an alternative to lumbar fusion in the treatment of lower back pain and reduces the risk of adjacent segment degeneration. Heterotopic ossification (HO) has been identified as a common complication following lumbar TDR. Purpose This systematic review aims to determine the prevalence, risk factors and clinical and radiological impact of HO following lumbar TDR. Study Design Systematic Review. Methods MEDLINE, Scopus, PubMed and Cochrane Central were searched for articles that referred to lumbar TDR and HO. The hits were assessed against inclusion and exclusion criteria. Data from each included study was extracted and analysed with respect to the study aims. Results Twenty-six studies were included in this review and the pooled prevalence of HO was estimated to be between 13.2% (participants) and 15.3% (vertebral levels). TDR clinical outcomes were not found to be reduced by HO and there was insufficient data to identify a given impact upon radiological outcomes. Age and follow up time were identified as potential risk factors for HO. Conclusions This review was hampered by inconsistencies in the reporting of HO across the studies. We therefore recommend that a set of guidelines should be produced to aid future researchers and reduce the risk of bias. | en_GB |
| dc.identifier.citation | Vol. 23, article 382 | en_GB |
| dc.identifier.doi | https://doi.org/10.1186/s12891-022-05322-9 | |
| dc.identifier.uri | http://hdl.handle.net/10871/129464 | |
| dc.identifier | ORCID: 0000-0002-2926-8022 (Akrami, Mohammad) | |
| dc.language.iso | en | en_GB |
| dc.publisher | BMC | en_GB |
| dc.rights | © The Author(s) 2022. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data | en_GB |
| dc.subject | Heterotopic ossification | en_GB |
| dc.subject | Lumbar spine | en_GB |
| dc.subject | Arthroplasty | en_GB |
| dc.subject | Spine surgery | en_GB |
| dc.subject | Disc/disk replacement | en_GB |
| dc.subject | Degenerative disc/disk | en_GB |
| dc.subject | Disc/disk disease | en_GB |
| dc.subject | Clinical outcome | en_GB |
| dc.subject | Systematic review | en_GB |
| dc.title | Impact of heterotopic ossifcation following lumbar total disk replacement: a systematic review | en_GB |
| dc.type | Article | en_GB |
| dc.date.available | 2022-04-26T13:31:32Z | |
| dc.identifier.issn | 1471-2474 | |
| dc.description | This is the final version. Available on open access from BMC via the DOI in this record | en_GB |
| dc.description | Availability of data and materials: All data generated and analysed during this study are included in this published article. | en_GB |
| dc.identifier.journal | BMC Musculoskeletal Disorders | en_GB |
| dc.relation.ispartof | BMC Musculoskeletal Disorders | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | en_GB |
| dcterms.dateAccepted | 2022-04-13 | |
| rioxxterms.version | VoR | en_GB |
| rioxxterms.licenseref.startdate | 2022-04-23 | |
| rioxxterms.type | Journal Article/Review | en_GB |
| refterms.dateFCD | 2022-04-26T12:59:49Z | |
| refterms.versionFCD | AM | |
| refterms.dateFOA | 2022-04-26T13:31:36Z | |
| refterms.panel | B | en_GB |
| refterms.dateFirstOnline | 2022-04-23 |
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