Clinical and Biomedical Sciences
Recent Submissions
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An axonal brake on striatal dopamine output by cholinergic interneurons
(Nature Research, 13 March 2025)Depolarization of axons is necessary for somatic action potentials to trigger axonal neurotransmitter release. Here we show that striatal cholinergic interneurons (ChIs) and nicotinic receptors (nAChRs) on mouse dopamine ... -
Two cases of neonatal hyperglycemia caused by a homozygous COQ9 stop-gain variant
(Wiley / Asian Association for the Study of Diabetes (AASD), 10 March 2025)Neonatal diabetes mellitus (NDM) is a monogenic condition diagnosed <6 months of age with >40 genetic causes. International guidelines recommend referral for genetic testing immediately after diagnosis since the genetic ... -
Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer
(Wiley / Federation of European Biochemical Societies, 19 February 2025)Prognostic transcriptomic signatures for prostate cancer (PCa) often overlook the cellular origin of expression changes, an important consideration given the heterogeneity of the disorder. Current clinicopathological factors ... -
Evidence of reduced birth-weight in Ukraine following the full-scale Russian invasion (dataset)
(University of Exeter, 5 February 2025)This is the dataset used for the Arbuzova et al. (2025) article "Evidence of reduced birth-weight in Ukraine following the full-scale Russian invasion". -
Transient cortical beta-frequency oscillations associated with contextual novelty in high density mouse EEG
(Nature Research, 23 January 2025)Beta-frequency oscillations (20–30 Hz) are prominent in both human and rodent electroencephalogram (EEG) recordings. Discrete epochs of beta (or Beta2) oscillations are prevalent in the hippocampus and other brain areas ...