Clinical and Biomedical Sciences
Recent Submissions
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Comparison of Bayesian approaches for developing prediction models in rare disease: application to the identification of patients with Maturity-Onset Diabetes of the Young
(BMC, 4 June 2024)Background Clinical prediction models can help identify high-risk patients and facilitate timely interventions. However, developing such models for rare diseases presents challenges due to the scarcity of affected patients ... -
SMIM1 absence is associated with reduced energy expenditure and excess weight
(Cell Press, 2024)Background Obesity rates have nearly tripled in the past 50 years, and by 2030, more than one billion individuals worldwide are projected to be obese. This creates a significant economic strain due to the associated ... -
Protein-truncating variants in BSN are associated with severe adult-onset obesity, type 2 diabetes and fatty liver disease.
(Nature Research, 4 April 2024)Obesity is a major risk factor for many common diseases and has a substantial heritable component. To identify new genetic determinants, we performed exome-sequence analyses for adult body mass index (BMI) in up to 587,027 ... -
Smartphone funduscopy for diabetic retinopathy screening
(Wiley, 16 April 2024)Aims: Smartphone funduscopy devices are comprised of lens devices connecting with smartphones and software applications to be used for mobile retinal image capturing and diagnosis of diabetic retinopathy. This is particularly ... -
Mismatch between HbA1c and fasting glucose in ethnic and gender groups
(Wiley, 16 April 2024)Aims: Previous research has shown that a mismatch can occur between HbA1c and fasting glucose, which may be increased in certain ethnic groups. This study aimed to combine the most recent NHANES data to create a larger ...