Health and Care Professions: Recent submissions
Now showing items 6-10 of 58
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Pharmacogenomic Determinants of Adverse Drug Effects: A Systematic Review and Meta-analysis
(International Institute of Anticancer Research, 26 August 2024)Background/Aim: Genomic variants can predispose individuals to adverse drug effects (ADEs), implying the potential for personalised therapy based on genetic data to prevent them. However, existing pharmacogenomic databases ... -
Pharmacogenetics of Toxicities Related to Endocrine Treatment in Breast Cancer: A Systematic Review and Meta-analysis
(International Institute of Anticancer Research, 27 August 2024)Background/Aim: Endocrine therapy is the standard treatment for hormone receptor-positive (HR+) breast cancer (BC). Yet, it is accompanied by treatment-related toxicities, leading to poor treatment adherence, high relapse, ... -
Haemochromatosis HFE genotypes and association with chondrocalcinosis: Early data from analysis in UK Biobank
(European Iron Club, 25 April 2024)The iron-overload disorder haemochromatosis is primarily caused by the homozygous HFE p.C282Y variant. Musculoskeletal changes including arthropathy and chondrocalcinosis (cartilage calcification) are well-recognised ... -
Point-of-Care Testing for SARS-CoV-2: A Prospective Study in a Primary Health Centre
(MDPI, 28 May 2023)Background: In 2020, health systems across the world responded to the COVID-19 pandemic by making rapid changes to reduce the risk of exposure in patients and healthcare professionals. The use of point-of-care tests (POCT) ... -
Does the Addition of Point-of-Care Testing Alter Antibiotic Prescribing Decisions When Patients Present with Acute Sore Throat to Primary Care? A Prospective Test of Change
(MDPI, 26 May 2024)Accurate clinical diagnosis of patients presenting to primary care settings with acute sore throat remains challenging, often resulting in the over-prescribing of antibiotics. Using point-of-care tests (POCTs) to differentiate ...