How well do Cognitive Behavioural Therapy and Behavioural Activation for depression repair anhedonia? A secondary analysis of the COBRA randomised controlled trial
dc.contributor.author | Alsayednasser, B | |
dc.contributor.author | Widnall, E | |
dc.contributor.author | O'Mahen, H | |
dc.contributor.author | Wright, K | |
dc.contributor.author | Warren, F | |
dc.contributor.author | Ladwa, A | |
dc.contributor.author | Khazanov, GK | |
dc.contributor.author | Byford, S | |
dc.contributor.author | Kuyken, W | |
dc.contributor.author | Watkins, E | |
dc.contributor.author | Ekers, D | |
dc.contributor.author | Reed, N | |
dc.contributor.author | Fletcher, E | |
dc.contributor.author | McMillan, D | |
dc.contributor.author | Farrand, P | |
dc.contributor.author | Richards, D | |
dc.contributor.author | Dunn, BD | |
dc.date.accessioned | 2022-08-30T13:39:46Z | |
dc.date.issued | 2022-09-27 | |
dc.date.updated | 2022-08-30T09:24:13Z | |
dc.description.abstract | A secondary analysis of the COBRA randomized controlled trial was conducted to examine how well Cognitive Behavioural Therapy (CBT) and Behavioural Activation (BA) repair anhedonia. Patients with current major depressive disorder (N = 440) were randomized to receive BA or CBT, and anhedonia and depression outcomes were measured after acute treatment (six months) and at two further follow up intervals (12 and 18 months). Anhedonia was assessed using the Snaith Hamilton Pleasure Scale (SHAPS; a measure of consummatory pleasure). Both CBT and BA led to significant improvements in anhedonia during acute treatment, with no significant difference between treatments. Participants remained above healthy population averages of anhedonia at six months, and there was no further significant improvement in anhedonia at 12-month or 18-month follow up. Greater baseline anhedonia severity predicted reduced repair of depression symptoms and fewer depression-free days across the follow-up period following both BA and CBT. The extent of anhedonia repair was less marked than the extent of depression repair across both treatment arms. These findings demonstrate that CBT and BA are similarly and only partially effective in treating anhedonia. Therefore, both therapies should be further refined or novel treatments should be developed in order better to treat anhedonia. | en_GB |
dc.description.sponsorship | National Institute for Health Research (NIHR) | en_GB |
dc.identifier.citation | Vol. 159, article 104185 | en_GB |
dc.identifier.doi | 10.1016/j.brat.2022.104185 | |
dc.identifier.uri | http://hdl.handle.net/10871/130610 | |
dc.identifier | ORCID: 0000-0002-0299-0920 (Dunn, Barnaby) | |
dc.language.iso | en | en_GB |
dc.publisher | Elsevier | en_GB |
dc.rights | © 2022 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/) | en_GB |
dc.subject | depression | en_GB |
dc.subject | anhedonia | en_GB |
dc.subject | behavioural activation | en_GB |
dc.subject | cognitive behavioural therapy | en_GB |
dc.subject | positive valence systems | en_GB |
dc.title | How well do Cognitive Behavioural Therapy and Behavioural Activation for depression repair anhedonia? A secondary analysis of the COBRA randomised controlled trial | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2022-08-30T13:39:46Z | |
dc.identifier.issn | 1873-622X | |
dc.description | This is the final version. Available on open access from Elsevier via the DOI in this record | en_GB |
dc.identifier.journal | Behaviour Research and Therapy | en_GB |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_GB |
dcterms.dateAccepted | 2022-08-19 | |
dcterms.dateSubmitted | 2021-11-09 | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2022-08-19 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2022-08-30T09:24:14Z | |
refterms.versionFCD | AM | |
refterms.dateFOA | 2022-10-05T12:41:02Z | |
refterms.panel | A | en_GB |
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Except where otherwise noted, this item's licence is described as © 2022 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)