Even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study.
dc.contributor.author | Evans, JP | |
dc.contributor.author | Maffulli, N | |
dc.contributor.author | Smith, C | |
dc.contributor.author | Watts, A | |
dc.contributor.author | Valderas, J | |
dc.contributor.author | Goodwin, V | |
dc.date.accessioned | 2022-09-27T09:05:45Z | |
dc.date.issued | 2021-11-25 | |
dc.date.updated | 2022-09-27T07:18:53Z | |
dc.description.abstract | BACKGROUND: Platelet-rich plasma (PRP) is widely used in the management of lateral elbow tendinopathy (LET) despite conflicting evidence on its effectiveness. With high levels of user experience, this study aimed to assess consensus amongst experts on its clinical use. METHODS: A three-round international Delphi study was conducted. Participants were invited through national society mailing lists and contact lists derived from a systematic search of the literature on PRP. In round one, a primary working group developed 40 statements on PRP preparation and clinical application. In rounds two and three, an international group of researchers on PRP and clinical users of the device scored their levels of agreement with the statements on a five-point scale. Consensus was defined as an interquartile range of ≤ 1. RESULTS: Consensus of agreement was only reached for 17/40 (42.5%) statements. For statements on PRP formulation, consensus of agreement was reached in 2/6 statements (33%). Only limited consensus on the contraindications, delivery strategy and delivery technique was achieved. CONCLUSION: Experts reached very limited consensus on the use of PRP in LET. High levels of user experience have not resulted in a convergence of opinion on the technical components of PRP formulation and delivery, substantiating the need for further studies and improved trial reporting. | en_GB |
dc.description.sponsorship | National Institute for Health Research | en_GB |
dc.format.extent | 47- | |
dc.format.medium | Electronic | |
dc.identifier.citation | Vol. 22, No. 1, article 47 | en_GB |
dc.identifier.doi | https://doi.org/10.1186/s10195-021-00608-5 | |
dc.identifier.uri | http://hdl.handle.net/10871/130983 | |
dc.identifier | ORCID: 0000-0003-0090-1012 (Evans, Jonathan P) | |
dc.identifier | ORCID: 0000-0003-3860-9607 (Goodwin, Vicki) | |
dc.identifier | ScopusID: 24334895100 (Goodwin, Vicki) | |
dc.language.iso | en | en_GB |
dc.publisher | Springer | en_GB |
dc.relation.url | https://www.ncbi.nlm.nih.gov/pubmed/34825302 | en_GB |
dc.rights | © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. | en_GB |
dc.subject | Consensus | en_GB |
dc.subject | Elbow | en_GB |
dc.subject | PRP | en_GB |
dc.subject | Platelet-rich plasma | en_GB |
dc.subject | Tendinopathy | en_GB |
dc.subject | Tennis elbow | en_GB |
dc.title | Even experts cannot agree on the optimal use of platelet-rich plasma in lateral elbow tendinopathy: an international Delphi study. | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2022-09-27T09:05:45Z | |
dc.identifier.issn | 1590-9921 | |
exeter.article-number | 47 | |
exeter.place-of-publication | Italy | |
dc.description | This is the final version. Available from Springer via the DOI in this record. | en_GB |
dc.identifier.eissn | 1590-9999 | |
dc.identifier.journal | Journal of Orthopaedics and Traumatology | en_GB |
dc.relation.ispartof | J Orthop Traumatol, 22(1) | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en_GB |
dcterms.dateAccepted | 2021-10-31 | |
dc.rights.license | CC BY | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2021-11-25 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2022-09-27T09:02:55Z | |
refterms.versionFCD | VoR | |
refterms.dateFOA | 2022-09-27T09:06:04Z | |
refterms.panel | A | en_GB |
refterms.dateFirstOnline | 2021-11-25 |
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