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dc.contributor.authorCox, NS
dc.contributor.authorEldridge, B
dc.contributor.authorRawlings, S
dc.contributor.authorDreger, J
dc.contributor.authorCorda, J
dc.contributor.authorHauser, J
dc.contributor.authorButton, B
dc.contributor.authorBishop, J
dc.contributor.authorNichols, A
dc.contributor.authorMiddleton, A
dc.contributor.authorWard, N
dc.contributor.authorDwyer, TJ
dc.contributor.authorDentice, R
dc.contributor.authorLazarus, R
dc.contributor.authorO'Halloran, P
dc.contributor.authorLee, JYT
dc.contributor.authorMellerick, C
dc.contributor.authorMackintosh, KA
dc.contributor.authorMcNarry, MA
dc.contributor.authorWilliams, CA
dc.contributor.authorHolland, AE
dc.date.accessioned2022-10-04T10:28:30Z
dc.date.issued2022-09-30
dc.date.updated2022-10-03T18:53:05Z
dc.description.abstractBackground Physical activity levels are known to decline following hospitalisation for people with cystic fibrosis (pwCF). However, optimal physical activity promotion strategies are unclear. This study investigated the effect of a web-based application (ActivOnline) in promoting physical activity in young pwCF. Methods Multicentre randomised controlled trial with assessor blinding and qualitative evaluation. People with CF (12–35 years) admitted to hospital for a respiratory cause were eligible and randomised to the 12-week ActivOnline intervention (AO) or usual care (UC). The primary outcome was change in device-based time spent in moderate-to-vigorous physical activity (MVPA) from baseline to post-intervention. Follow-up was at 6 months from hospital discharge when qualitative evaluation was undertaken. Results 107 participants were randomised to AO (n=52) or UC (n=55). Sixty-three participants (59%) contributed to the intention-to-treat analysis. Mean (SD) age was 21 (6) years (n=46, <18 years). At baseline, physical activity levels were high in both groups (AO 102 (52) vs UC 127 (73) min/day). There was no statistically significant difference in MVPA between groups at either timepoint (post-intervention mean difference (95% CI) −14 mins (−45 to 16)). Uptake of the intervention was low with only 40% (n=21) of participants accessing the web application. Conclusion A web-based application, including individualised goal setting, real-time feedback and motivation for behavioural change, was no better than usual care at promoting physical activity in young pwCF following hospital discharge. High levels of baseline physical activity levels in both groups, and limited engagement with the intervention, suggest alternative strategies may be necessary to identify and support young pwCF who would benefit from enhanced physical activity. Trial registration number ACTRN12617001009303, 13 July 13 2017.en_GB
dc.description.sponsorshipCystic Fibrosis Trusten_GB
dc.format.extent1-8
dc.identifier.citationPublished online 30 September 2022en_GB
dc.identifier.doi10.1136/thorax-2022-218702
dc.identifier.grantnumber008en_GB
dc.identifier.urihttp://hdl.handle.net/10871/131080
dc.identifierORCID: 0000-0002-1740-6248 (Williams, Craig)
dc.identifierScopusID: 57201609242 (Williams, Craig)
dc.identifierResearcherID: AAQ-8954-2020 (Williams, Craig)
dc.language.isoenen_GB
dc.publisherBMJ Publishing Group / British Thoracic Societyen_GB
dc.rights© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ. This version is made available under the CC-BY-NC 4.0 license: https://creativecommons.org/licenses/by-nc/4.0/  en_GB
dc.titleWeb-based physical activity promotion in young people with CF: a randomised controlled trialen_GB
dc.typeArticleen_GB
dc.date.available2022-10-04T10:28:30Z
dc.identifier.issn1468-3296
dc.descriptionThis is the author accepted manuscript. The final version is available from BMJ Publishing Group via the DOI in this recorden_GB
dc.descriptionData availability statement: Data are available on reasonable request. Data requests should, in the first instance, be addressed to Professor Anne Holland (anne.holland@monash.edu). Access to data will be subject to approval by the coordinating principal investigator and relevant Human Research Ethics Committee.en_GB
dc.identifier.journalThoraxen_GB
dc.relation.ispartofThorax
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/  en_GB
dcterms.dateAccepted2022-09-13
dcterms.dateSubmitted2022-01-11
rioxxterms.versionAMen_GB
rioxxterms.licenseref.startdate2022-09-30
rioxxterms.typeJournal Article/Reviewen_GB
refterms.dateFCD2022-10-03T18:53:07Z
refterms.versionFCDAM
refterms.dateFOA2022-10-04T10:29:18Z
refterms.panelAen_GB
refterms.dateFirstOnline2022-09-30


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© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ. This version is made available under the CC-BY-NC 4.0 license: https://creativecommons.org/licenses/by-nc/4.0/  
Except where otherwise noted, this item's licence is described as © Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ. This version is made available under the CC-BY-NC 4.0 license: https://creativecommons.org/licenses/by-nc/4.0/