A compositional analysis of physical activity, sedentary time, and sleep and associated health outcomes in children and adults with Cystic Fibrosis.
dc.contributor.author | Bianchim, MS | |
dc.contributor.author | McNarry, MA | |
dc.contributor.author | Holland, A | |
dc.contributor.author | Cox, NS | |
dc.contributor.author | Dreger, J | |
dc.contributor.author | Barker, AR | |
dc.contributor.author | Williams, CA | |
dc.contributor.author | Denford, S | |
dc.contributor.author | Mackintosh, KA | |
dc.date.accessioned | 2022-10-19T13:24:20Z | |
dc.date.issued | 2022-04-23 | |
dc.date.updated | 2022-10-19T12:36:04Z | |
dc.description.abstract | This study sought to investigate the association of light physical activity (LPA), moderate-to-vigorous physical activity (MVPA), sedentary time (SED), and sleep with lung function in children and adults with CF. In total, 86 children (41 females; 13.6 ± 2.8 years; FEV1%predicted: 86 ± 1%) and 43 adults (21 females; 24.6 ± 4.7 years; FEV1%predicted: 63 ± 21%) with CF participated in this study. Wrist-worn accelerometery was used to assess PA, SED and sleep. Compositional linear regression models were conducted following normalisation via isometric log-ratio transformations. Sequential binary partitioning was applied to investigate the impact of reallocating 10 to 30 min between each behaviour on FEV1%predicted. A decline in FEV1%predicted was predicted with the reallocation of 30 min from MVPA to SED or LPA or sleep to any other behaviour in children (-3.04--0.005%) and adults (-3.58--0.005%). Conversely, improvements in FEV1%predicted were predicted when 30 min was reallocated to MVPA from LPA or SED in children (0.12-1.59%) and adults (0.77-2.10%), or when 30 min was reallocated to sleep from any other behaviour in both children (0.23-2.56%) and adults (1.08-3.58%). This study supports the importance of MVPA and sleep for maintaining and promoting lung function in people with CF. | en_GB |
dc.description.sponsorship | Cystic Fibrosis Trust UK | en_GB |
dc.identifier.citation | Vol. 19, No. 9, article 5155 | en_GB |
dc.identifier.doi | https://doi.org/10.3390/ijerph19095155 | |
dc.identifier.grantnumber | RP-PG-0108-10011 | en_GB |
dc.identifier.uri | http://hdl.handle.net/10871/131333 | |
dc.identifier | ORCID: 0000-0001-8610-5417 (Barker, Alan R) | |
dc.identifier | ORCID: 0000-0002-1740-6248 (Williams, Craig A) | |
dc.language.iso | en | en_GB |
dc.publisher | MDPI | en_GB |
dc.relation.url | https://www.ncbi.nlm.nih.gov/pubmed/35564550 | en_GB |
dc.rights | © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | en_GB |
dc.subject | composition | en_GB |
dc.subject | compositional analysis | en_GB |
dc.subject | lung function | en_GB |
dc.subject | moderate-to-vigorous physical activity | en_GB |
dc.subject | movement behaviours | en_GB |
dc.subject | youth | en_GB |
dc.title | A compositional analysis of physical activity, sedentary time, and sleep and associated health outcomes in children and adults with Cystic Fibrosis. | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2022-10-19T13:24:20Z | |
dc.identifier.issn | 1661-7827 | |
exeter.article-number | 5155 | |
exeter.place-of-publication | Switzerland | |
dc.description | This is the final version. Available on open access from MDPI via the DOI in this record. | en_GB |
dc.description | Data Availability Statement: The datasets generated and/or analysed during the current study are not publicly available due to GDPR regulations and to protect individual privacy but are available from the corresponding author on reasonable request. | en_GB |
dc.identifier.eissn | 1660-4601 | |
dc.identifier.journal | International Journal of Environmental Research and Public Health | en_GB |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_GB |
dcterms.dateAccepted | 2022-04-20 | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2022-04-23 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2022-10-19T13:20:35Z | |
refterms.versionFCD | VoR | |
refterms.dateFOA | 2022-10-19T13:24:26Z | |
refterms.panel | A | en_GB |
refterms.dateFirstOnline | 2022-04-23 |
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Except where otherwise noted, this item's licence is described as © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).