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dc.contributor.authorBianchim, MS
dc.contributor.authorMcNarry, MA
dc.contributor.authorHolland, A
dc.contributor.authorCox, NS
dc.contributor.authorDreger, J
dc.contributor.authorBarker, AR
dc.contributor.authorWilliams, CA
dc.contributor.authorDenford, S
dc.contributor.authorMackintosh, KA
dc.date.accessioned2022-10-19T13:24:20Z
dc.date.issued2022-04-23
dc.date.updated2022-10-19T12:36:04Z
dc.description.abstractThis study sought to investigate the association of light physical activity (LPA), moderate-to-vigorous physical activity (MVPA), sedentary time (SED), and sleep with lung function in children and adults with CF. In total, 86 children (41 females; 13.6 ± 2.8 years; FEV1%predicted: 86 ± 1%) and 43 adults (21 females; 24.6 ± 4.7 years; FEV1%predicted: 63 ± 21%) with CF participated in this study. Wrist-worn accelerometery was used to assess PA, SED and sleep. Compositional linear regression models were conducted following normalisation via isometric log-ratio transformations. Sequential binary partitioning was applied to investigate the impact of reallocating 10 to 30 min between each behaviour on FEV1%predicted. A decline in FEV1%predicted was predicted with the reallocation of 30 min from MVPA to SED or LPA or sleep to any other behaviour in children (-3.04--0.005%) and adults (-3.58--0.005%). Conversely, improvements in FEV1%predicted were predicted when 30 min was reallocated to MVPA from LPA or SED in children (0.12-1.59%) and adults (0.77-2.10%), or when 30 min was reallocated to sleep from any other behaviour in both children (0.23-2.56%) and adults (1.08-3.58%). This study supports the importance of MVPA and sleep for maintaining and promoting lung function in people with CF.en_GB
dc.description.sponsorshipCystic Fibrosis Trust UKen_GB
dc.identifier.citationVol. 19, No. 9, article 5155en_GB
dc.identifier.doihttps://doi.org/10.3390/ijerph19095155
dc.identifier.grantnumberRP-PG-0108-10011en_GB
dc.identifier.urihttp://hdl.handle.net/10871/131333
dc.identifierORCID: 0000-0001-8610-5417 (Barker, Alan R)
dc.identifierORCID: 0000-0002-1740-6248 (Williams, Craig A)
dc.language.isoenen_GB
dc.publisherMDPIen_GB
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pubmed/35564550en_GB
dc.rights© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).en_GB
dc.subjectcompositionen_GB
dc.subjectcompositional analysisen_GB
dc.subjectlung functionen_GB
dc.subjectmoderate-to-vigorous physical activityen_GB
dc.subjectmovement behavioursen_GB
dc.subjectyouthen_GB
dc.titleA compositional analysis of physical activity, sedentary time, and sleep and associated health outcomes in children and adults with Cystic Fibrosis.en_GB
dc.typeArticleen_GB
dc.date.available2022-10-19T13:24:20Z
dc.identifier.issn1661-7827
exeter.article-number5155
exeter.place-of-publicationSwitzerland
dc.descriptionThis is the final version. Available on open access from MDPI via the DOI in this record. en_GB
dc.descriptionData Availability Statement: The datasets generated and/or analysed during the current study are not publicly available due to GDPR regulations and to protect individual privacy but are available from the corresponding author on reasonable request.en_GB
dc.identifier.eissn1660-4601
dc.identifier.journalInternational Journal of Environmental Research and Public Healthen_GB
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_GB
dcterms.dateAccepted2022-04-20
rioxxterms.versionVoRen_GB
rioxxterms.licenseref.startdate2022-04-23
rioxxterms.typeJournal Article/Reviewen_GB
refterms.dateFCD2022-10-19T13:20:35Z
refterms.versionFCDVoR
refterms.dateFOA2022-10-19T13:24:26Z
refterms.panelAen_GB
refterms.dateFirstOnline2022-04-23


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© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Except where otherwise noted, this item's licence is described as © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).