Research needs for optimising wastewater-based epidemiology monitoring for public health protection
dc.contributor.author | Robins, K | |
dc.contributor.author | Leonard, AFC | |
dc.contributor.author | Farkas, K | |
dc.contributor.author | Graham, DW | |
dc.contributor.author | Jones, DL | |
dc.contributor.author | Kasprzyk-Hordern, B | |
dc.contributor.author | Bunce, JT | |
dc.contributor.author | Grimsley, JMS | |
dc.contributor.author | Wade, MJ | |
dc.contributor.author | Zealand, AM | |
dc.contributor.author | McIntyre-Nolan, S | |
dc.date.accessioned | 2022-11-03T14:01:57Z | |
dc.date.issued | 2022-08-12 | |
dc.date.updated | 2022-11-03T13:16:35Z | |
dc.description.abstract | Wastewater-based epidemiology (WBE) is an unobtrusive method used to observe patterns in illicit drug use, poliovirus, and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The pandemic and need for surveillance measures have led to the rapid acceleration of WBE research and development globally. With the infrastructure available to monitor SARS-CoV-2 from wastewater in 58 countries globally, there is potential to expand targets and applications for public health protection, such as other viral pathogens, antimicrobial resistance (AMR), pharmaceutical consumption, or exposure to chemical pollutants. Some applications have been explored in academic research but are not used to inform public health decision-making. We reflect on the current knowledge of WBE for these applications and identify barriers and opportunities for expanding beyond SARS-CoV-2. This paper critically reviews the applications of WBE for public health and identifies the important research gaps for WBE to be a useful tool in public health. It considers possible uses for pathogenic viruses, AMR, and chemicals. It summarises the current evidence on the following: (1) the presence of markers in stool and urine; (2) environmental factors influencing persistence of markers in wastewater; (3) methods for sample collection and storage; (4) prospective methods for detection and quantification; (5) reducing uncertainties; and (6) further considerations for public health use. | en_GB |
dc.description.sponsorship | Natural Environment Research Council (NERC) | en_GB |
dc.description.sponsorship | Engineering and Physical Sciences Research Council (EPSRC) | en_GB |
dc.format.extent | 1284-1313 | |
dc.format.medium | ||
dc.identifier.citation | Vol. 20(9), pp. 1284-1313 | en_GB |
dc.identifier.doi | https://doi.org/10.2166/wh.2022.026 | |
dc.identifier.grantnumber | NE/V010441/1 | en_GB |
dc.identifier.grantnumber | EP/V028499/1 | en_GB |
dc.identifier.uri | http://hdl.handle.net/10871/131605 | |
dc.identifier | ORCID: 0000-0002-8231-602X (Leonard, Anne FC) | |
dc.language.iso | en | en_GB |
dc.publisher | IWA Publishing / World Health Organization | en_GB |
dc.relation.url | https://www.ncbi.nlm.nih.gov/pubmed/36170187 | en_GB |
dc.rights | © 2022 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (CC BY 4.0), which permits copying, adaptation and redistribution, provided the original work is properly cited (http://creativecommons.org/licenses/by/4.0/). | en_GB |
dc.subject | Anti-Infective Agents | en_GB |
dc.subject | COVID-19 | en_GB |
dc.subject | Environmental Pollutants | en_GB |
dc.subject | Humans | en_GB |
dc.subject | Illicit Drugs | en_GB |
dc.subject | Pharmaceutical Preparations | en_GB |
dc.subject | Public Health | en_GB |
dc.subject | SARS-CoV-2 | en_GB |
dc.subject | Waste Water | en_GB |
dc.subject | Wastewater-Based Epidemiological Monitoring | en_GB |
dc.title | Research needs for optimising wastewater-based epidemiology monitoring for public health protection | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2022-11-03T14:01:57Z | |
dc.identifier.issn | 1477-8920 | |
exeter.place-of-publication | England | |
dc.description | This is the final version. Available on open access from IWA Publishing via the DOI in this record | en_GB |
dc.description | Data availability statement: All relevant data are included in the paper or its Supplementary Information. | en_GB |
dc.identifier.eissn | 1996-7829 | |
dc.identifier.journal | Journal of Water and Health | en_GB |
dc.relation.ispartof | J Water Health, 20(9) | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_GB |
dcterms.dateAccepted | 2022-07-28 | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2022-08-12 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2022-11-03T13:58:10Z | |
refterms.versionFCD | VoR | |
refterms.dateFOA | 2022-11-03T14:02:02Z | |
refterms.panel | A | en_GB |
refterms.dateFirstOnline | 2022-08-12 |
Files in this item
This item appears in the following Collection(s)
Except where otherwise noted, this item's licence is described as © 2022 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (CC BY 4.0), which permits copying, adaptation and redistribution, provided the original work is properly cited (http://creativecommons.org/licenses/by/4.0/).