Fundamentals of Bowel Cancer for Biomedical Engineers
dc.contributor.author | Tian, J | |
dc.contributor.author | Afebu, KO | |
dc.contributor.author | Bickerdike, A | |
dc.contributor.author | Liu, Y | |
dc.contributor.author | Prasad, S | |
dc.contributor.author | Nelson, BJ | |
dc.date.accessioned | 2023-02-15T14:39:55Z | |
dc.date.issued | 2023-02-14 | |
dc.date.updated | 2023-02-15T03:41:51Z | |
dc.description.abstract | Bowel cancer is a multifactorial disease arising from a combination of genetic predisposition and environmental factors. Detection of bowel cancer and its precursor lesions is predominantly performed by either visual inspection of the colonic mucosa during endoscopy or cross-sectional imaging. Most cases are diagnosed when the cancer is already at an advanced stage. These modalities are less reliable for detecting lesions at the earliest stages, when they are typically small or flat. Removal of lesions at the earliest possible stage reduces the risk of cancer death, which is largely due to a reduced risk of subsequent metastasis. In this review, we summarised the origin of bowel cancer and the mechanism of its metastasis. In particular, we reviewed a broad spectrum of literatures covering the biomechanics of bowel cancer and its measurement techniques that are pertinent to the successful development of a bowel cancer diagnostic device. We also reviewed existing bowel cancer diagnostic techniques that are available for clinical use. Finally, we outlined current clinical needs and highlighted the potential roles of medical robotics on early bowel cancer diagnosis. | en_GB |
dc.description.sponsorship | Engineering and Physical Sciences Research Council (EPSRC) | en_GB |
dc.description.sponsorship | China Scholarship Council | |
dc.identifier.citation | Published online 14 February 2023 | en_GB |
dc.identifier.doi | 10.1007/s10439-023-03155-8 | |
dc.identifier.grantnumber | EP/R043698/1 | en_GB |
dc.identifier.grantnumber | EP/V047868/1 | en_GB |
dc.identifier.grantnumber | 201908060172 | |
dc.identifier.grantnumber | 710076422 | |
dc.identifier.uri | http://hdl.handle.net/10871/132482 | |
dc.identifier | ORCID: 0000-0003-3867-5137 (Liu, Yang) | |
dc.language.iso | en | en_GB |
dc.publisher | Springer | en_GB |
dc.rights | © 2023. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. | en_GB |
dc.subject | Bowel cancer | |
dc.subject | Bowel cancer biomechanics | |
dc.subject | Bowel cancer diagnosis | |
dc.subject | Bowel cancer metastasis | |
dc.subject | Colorectal cancer | |
dc.title | Fundamentals of Bowel Cancer for Biomedical Engineers | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2023-02-15T14:39:55Z | |
dc.identifier.issn | 1573-9686 | |
dc.description | This is the final version. Available on open access from Springer via the DOI in this record | en_GB |
dc.identifier.journal | Annals of Biomedical Engineering | en_GB |
dc.relation.ispartof | Annals of Biomedical Engineering | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_GB |
dcterms.dateAccepted | 2023-01-21 | |
dcterms.dateSubmitted | 2022-12-28 | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2023-02-14 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2023-02-15T03:41:53Z | |
refterms.versionFCD | AM | |
refterms.dateFOA | 2023-02-15T14:39:58Z | |
refterms.panel | B | en_GB |
refterms.dateFirstOnline | 2023-02-14 |
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Except where otherwise noted, this item's licence is described as © 2023. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.