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dc.contributor.authorTian, J
dc.contributor.authorLiu, Y
dc.contributor.authorBi, H
dc.contributor.authorPrasad, S
dc.contributor.authorLiu, C
dc.date.accessioned2023-09-25T08:42:09Z
dc.date.issued2023-09-23
dc.date.updated2023-09-24T19:09:15Z
dc.description.abstractTissue’s mechanical properties, such as stiffness, are critical biomarkers that could be utilised to detect early stages of malignant transformation and distinguish between healthy and abnormal tissues. This paper studied a new method by using a capsule robot to evaluate the stiffness of bowel tumour for early bowel cancer detection and staging. Hertz contact theory was used to model capsule-tumour contact in an intestinal environment. Both lateral and vertical contacts were performed with finite element (FE) and experimental validations. Young’s moduli of bowel tumours obtained by the proposed models were applied to FE models and then generated force–displacement curves to compare with experiments. Our comparative analysis shows that FE results are in good agreement with experimental results. The proposed method can be potentially used in real time for detecting early bowel cancer by using a capsule robot when self-propelling in the bowel.en_GB
dc.description.sponsorshipEngineering and Physical Sciences Research Council (EPSRC)en_GB
dc.description.sponsorshipRoyal Societyen_GB
dc.description.sponsorshipChina Scholarship Councilen_GB
dc.description.sponsorshipNational Natural Science Foundation of Chinaen_GB
dc.format.extent105148-105148
dc.identifier.citationArticle 105148en_GB
dc.identifier.doihttps://doi.org/10.1016/j.euromechsol.2023.105148
dc.identifier.grantnumberEP/V047868/1en_GB
dc.identifier.grantnumberIEC/NSFC/201059en_GB
dc.identifier.grantnumber201908060172en_GB
dc.identifier.grantnumber202006290118en_GB
dc.identifier.grantnumber11932001en_GB
dc.identifier.urihttp://hdl.handle.net/10871/134079
dc.identifierORCID: 0000-0003-3867-5137 (Liu, Yang)
dc.identifierScopusID: 55199382800 (Liu, Yang)
dc.identifierResearcherID: ABD-4124-2021 | K-1976-2015 (Liu, Yang)
dc.language.isoenen_GB
dc.publisherElsevieren_GB
dc.rights© 2023 The Author(s). Published by Elsevier Masson SAS. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)en_GB
dc.subjectYoung’s modulusen_GB
dc.subjectBowel canceren_GB
dc.subjectCapsule roboten_GB
dc.subjectHertz contact theoryen_GB
dc.subjectBiomechanicsen_GB
dc.titleModelling and experimental investigation of capsule-tumour contact for early bowel cancer detectionen_GB
dc.typeArticleen_GB
dc.date.available2023-09-25T08:42:09Z
dc.identifier.issn0997-7538
exeter.article-number105148
dc.descriptionThis is the author accepted manuscript. The final version is available on open access from Elsevier via the DOI in this recorden_GB
dc.descriptionData availability: Data will be made available on request.en_GB
dc.identifier.journalEuropean Journal of Mechanics - A/Solidsen_GB
dc.relation.ispartofEuropean Journal of Mechanics - A/Solids
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_GB
dcterms.dateAccepted2023-09-21
rioxxterms.versionAMen_GB
rioxxterms.licenseref.startdate2023-09-23
rioxxterms.typeJournal Article/Reviewen_GB
refterms.dateFCD2023-09-25T08:38:50Z
refterms.versionFCDAM
refterms.dateFOA2023-09-25T08:42:12Z
refterms.panelBen_GB


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© 2023 The Author(s). Published by Elsevier Masson SAS. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)
Except where otherwise noted, this item's licence is described as © 2023 The Author(s). Published by Elsevier Masson SAS. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)