The Role of Diet in the Cardiovascular Health of Childhood Cancer Survivors - A Systematic Review
dc.contributor.author | Li, R | |
dc.contributor.author | Barker, AR | |
dc.contributor.author | Vlachopoulos, D | |
dc.contributor.author | Paris, D | |
dc.contributor.author | Schindera, C | |
dc.contributor.author | Belle, FN | |
dc.contributor.author | Revuelta Iniesta, R | |
dc.date.accessioned | 2024-05-03T13:37:55Z | |
dc.date.issued | 2024-04-27 | |
dc.date.updated | 2024-04-30T20:35:33Z | |
dc.description.abstract | Background: Childhood cancer survivors (CCSs) face an increased risk of cardiovascular disease (CVD). This systematic review aims to provide the first synthesis of observational and interventional studies on the relationship between diet and cardiovascular health in CCSs. Methods: A comprehensive search was conducted for studies published between 1990 and July 2023 in PubMed, MEDLINE, CINAHL, Child Development & Adolescent Studies, and Cochrane Library. Eligible studies included observational and interventional studies examining the associations or effects of dietary factors on CVD incidence, cardiac dysfunction, or CVD risk factors in CCSs diagnosed before age 25 years. Results: Ten studies met the inclusion criteria (nine observational and one interventional). Collectively, they comprised 3485 CCSs (male, 1734; female, 1751). The outcomes examined across observational studies included characteristics of obesity, diabetes biomarkers, hypertension indicators, dyslipidaemia biomarkers, and metabolic syndrome. The evidence suggested that greater adherence to healthy diets was associated with lower body mass index, blood pressure, glucose, and triglycerides and higher high-density lipoprotein cholesterol. The 12-week lifestyle intervention study in childhood leukaemia survivors found no impact on obesity indicators. Conclusion: The review results indicate the potentially protective effects of healthy diets. However, the available research remains preliminary and limited, underscoring the need for more rigorous, adequately powered studies. | en_GB |
dc.description.sponsorship | China Scholarship Council | en_GB |
dc.description.sponsorship | Stiftung für krebskranke Kinder, Regio Basiliensis | en_GB |
dc.description.sponsorship | University of Basel Research Fund for Excellent Junior Researchers | en_GB |
dc.format.extent | 1315-1315 | |
dc.identifier.citation | Vol. 16(9), article 1315 | en_GB |
dc.identifier.doi | https://doi.org/10.3390/nu16091315 | |
dc.identifier.uri | http://hdl.handle.net/10871/135859 | |
dc.identifier | ORCID: 0009-0009-2621-1969 (Li, Ruijie) | |
dc.identifier | ORCID: 0000-0001-8610-5417 (Barker, Alan R) | |
dc.identifier | ORCID: 0000-0002-5534-7146 (Revuelta Iniesta, Raquel) | |
dc.language.iso | en | en_GB |
dc.publisher | MDPI | en_GB |
dc.rights | © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | en_GB |
dc.subject | diet | en_GB |
dc.subject | diet recommendations | en_GB |
dc.subject | childhood cancer survivors | en_GB |
dc.subject | cardiovascular diseases | en_GB |
dc.subject | cardiovascular disease risk factors | en_GB |
dc.subject | cardiac dysfunction | en_GB |
dc.title | The Role of Diet in the Cardiovascular Health of Childhood Cancer Survivors - A Systematic Review | en_GB |
dc.type | Article | en_GB |
dc.date.available | 2024-05-03T13:37:55Z | |
dc.description | This is the final version. Available on open access from MDPI via the DOI in this record | en_GB |
dc.identifier.eissn | 2072-6643 | |
dc.identifier.journal | Nutrients | en_GB |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | en_GB |
dcterms.dateAccepted | 2024-04-25 | |
dcterms.dateSubmitted | 2024-03-27 | |
rioxxterms.version | VoR | en_GB |
rioxxterms.licenseref.startdate | 2024-04-27 | |
rioxxterms.type | Journal Article/Review | en_GB |
refterms.dateFCD | 2024-04-30T20:35:50Z | |
refterms.versionFCD | AM | |
refterms.dateFOA | 2024-05-03T13:37:59Z | |
refterms.panel | A | en_GB |
refterms.dateFirstOnline | 2024-04-27 |
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Except where otherwise noted, this item's licence is described as © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).