The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes.
Richardson, Sarah J.; Willcox, A; Bone, AJ; et al.Foulis, Alan K.; Morgan, Noel G.
Date: 1 June 2009
Journal
Diabetologia
Publisher
Springer Verlag
Publisher DOI
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Abstract
Evidence that the beta cells of human patients with type 1 diabetes can be infected with enterovirus is accumulating, but it remains unclear whether such infections occur at high frequency and are important in the disease process. We have now assessed the prevalence of enteroviral capsid protein vp1 (vp1) staining in a large cohort of ...
Evidence that the beta cells of human patients with type 1 diabetes can be infected with enterovirus is accumulating, but it remains unclear whether such infections occur at high frequency and are important in the disease process. We have now assessed the prevalence of enteroviral capsid protein vp1 (vp1) staining in a large cohort of autopsy pancreases of recent-onset type 1 diabetic patients and a range of controls.
Institute of Biomedical & Clinical Science
Collections of Former Colleges
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