The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes.
Richardson, Sarah J.
Foulis, Alan K.
Morgan, Noel G.
Evidence that the beta cells of human patients with type 1 diabetes can be infected with enterovirus is accumulating, but it remains unclear whether such infections occur at high frequency and are important in the disease process. We have now assessed the prevalence of enteroviral capsid protein vp1 (vp1) staining in a large cohort of autopsy pancreases of recent-onset type 1 diabetic patients and a range of controls.
addresses: Institute of Biomedical and Clinical Sciences, Peninsula Medical School, Plymouth, UK.
The final publication is available at link.springer.com/article/10.1007%2Fs00125-009-1276-0
Diabetologia, 2009, Vol. 52, Issue 6, pp. 1143 - 1151
Place of publication