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Evidence of increased islet cell proliferation in patients with recent-onset type 1 diabetes.

dc.contributor.authorWillcox, A
dc.contributor.authorRichardson, Sarah J.
dc.contributor.authorBone, AJ
dc.contributor.authorFoulis, Alan K.
dc.contributor.authorMorgan, Noel G.
dc.date.accessioned2013-10-17T11:22:50Z
dc.date.issued2010-09
dc.description.abstractIn adults, the rate of beta cell replication is normally very low, but recent evidence suggests that it may increase during insulitis. We therefore studied tissue from donors with recent-onset type 1 diabetes to establish whether islet cell proliferation is increased during the disease process.en_GB
dc.identifier.citationDiabetologia, 2010, Vol. 53, Issue 9, pp. 2020 - 2028en_GB
dc.identifier.doi10.1007/s00125-010-1817-6
dc.identifier.urihttp://hdl.handle.net/10871/13815
dc.language.isoenen_GB
dc.publisherSpringer Verlagen_GB
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/20532863en_GB
dc.relation.urlhttp://link.springer.com/article/10.1007%2Fs00125-010-1817-6en_GB
dc.subjectAdolescenten_GB
dc.subjectAdulten_GB
dc.subjectCell Cycle Proteinsen_GB
dc.subjectCell Proliferationen_GB
dc.subjectChilden_GB
dc.subjectChild, Preschoolen_GB
dc.subjectDiabetes Mellitus, Type 1en_GB
dc.subjectFemaleen_GB
dc.subjectGlucagon-Secreting Cellsen_GB
dc.subjectHumansen_GB
dc.subjectImmunohistochemistryen_GB
dc.subjectInfanten_GB
dc.subjectInsulin-Secreting Cellsen_GB
dc.subjectKi-67 Antigenen_GB
dc.subjectMaleen_GB
dc.subjectNuclear Proteinsen_GB
dc.subjectPancreasen_GB
dc.subjectYoung Adulten_GB
dc.titleEvidence of increased islet cell proliferation in patients with recent-onset type 1 diabetes.en_GB
dc.typeArticleen_GB
dc.date.available2013-10-17T11:22:50Z
dc.identifier.issn0012-186X
exeter.place-of-publicationGermany
dc.descriptionaddresses: Institute of Biomedical and Clinical Science, Peninsula College of Medicine and Dentistry (University of Exeter), Tamar Science Park, Derriford, Plymouth, UK.en_GB
dc.descriptionThe final publication is available at link.springer.com/article/10.1007%2Fs00125-010-1817-6en_GB
dc.identifier.journalDiabetologiaen_GB


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